Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11329134 | 1.00 | SMN1; SMN2 (0.44) | SMN1; SMN2TP53LMNAPKMKMT2A | |
| SCHEMBL6878184 | 0.79 | CES2 (0.47) | SMN1; SMN2TP53LMNAPKMKMT2A | |
| SCHEMBL6878186 | 0.79 | CES2 (0.47) | SMN1; SMN2TP53LMNAPKMKMT2A | |
| SCHEMBL9143119 | 0.79 | CES2 (0.47) | SMN1; SMN2TP53LMNAPKMKMT2A | |
| SCHEMBL11134142 | 0.77 | SMN1; SMN2 (0.51) | SMN1; SMN2TP53LMNAPKMKMT2A | |
| SCHEMBL11327758 | 0.76 | PGR (0.36) | SMN1; SMN2LMNAPKMALDH1A1TSHR | |
| SCHEMBL11327754 | 0.76 | PGR (0.36) | SMN1; SMN2LMNAPKMALDH1A1TSHR | |
| SCHEMBL11535484 | 0.76 | SMN1; SMN2 (0.49) | SMN1; SMN2TP53LMNAPKMKMT2A | |
| SCHEMBL9864807 | 0.76 | PTPN1 (0.41) | SMN1; SMN2PKMKMT2AALDH1A1HPGD | |
| SCHEMBL9864813 | 0.76 | PTPN1 (0.41) | SMN1; SMN2PKMKMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4256739-A | 7β-Amino-3-thio-3-cephem-4-carboxylic acid compounds, and antibacterial compositions and methods using them | CIBA-GEIGY CORPORATION (US) | 1981-03-17 | — | — | US | disclosed |