Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11134142 | 0.88 | SMN1; SMN2 (0.51) | SMN1; SMN2TP53LMNAPTPN1MAPT | |
| SCHEMBL11134139 | 0.88 | SMN1; SMN2 (0.47) | SMN1; SMN2TP53LMNAPTPN1MAPT | |
| SCHEMBL11134141 | 0.88 | SMN1; SMN2 (0.47) | SMN1; SMN2TP53LMNAPTPN1MAPT | |
| SCHEMBL2812477 | 0.80 | CES2 (0.52) | SMN1; SMN2TP53PTPN1RAB9ANPC1 | |
| SCHEMBL11457463 | 0.80 | CES2 (0.52) | SMN1; SMN2TP53PTPN1RAB9ANPC1 | |
| SCHEMBL4609969 | 0.80 | CES2 (0.52) | SMN1; SMN2TP53PTPN1RAB9ANPC1 | |
| Ammonia Solution, Strong SCHEMBL28417876 | 0.79 | CES2 (0.50) | SMN1; SMN2TP53PTPN1RAB9ANPC1 | |
| Ammonia Solution, Strong SCHEMBL4752940 | 0.79 | CES2 (0.50) | SMN1; SMN2TP53PTPN1RAB9ANPC1 | |
| Ammonia Solution, Strong SCHEMBL5211578 | 0.79 | CES2 (0.50) | SMN1; SMN2TP53PTPN1RAB9ANPC1 | |
| SCHEMBL11329136 | 0.76 | SMN1; SMN2 (0.44) | SMN1; SMN2TP53LMNAPTPN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4138555-A | BACTERICIDES | GLAXO LABORATORIES, LIMITED (GB) | 1979-02-06 | — | — | US | disclosed |