Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | F13A1 | P00488 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11135725 | 0.80 | S1PR2 (0.47) | LTB4RFFAR1 | |
| SCHEMBL11133594 | 0.79 | CPB2 (0.50) | LMNAFFAR1 | |
| SCHEMBL11131232 | 0.78 | ADRA1A (0.57) | ADRA1AKDM4EF13A1MAPK1HIF1A | |
| SCHEMBL11135739 | 0.78 | ADRA1A (0.57) | ADRA1AKDM4EF13A1MAPK1HIF1A | |
| SCHEMBL11471927 | 0.78 | KDM4E (0.68) | KDM4EF13A1HIF1ALMNAHPGD | |
| SCHEMBL13670627 | 0.78 | MTNR1A (0.54) | FOLH1KDM4EMTNR1AMTNR1BMAPK1 | |
| SCHEMBL11134031 | 0.77 | CPB2 (0.48) | FFAR1 | |
| SCHEMBL25496786 | 0.75 | MTNR1A (0.67) | KDM4EMTNR1AMTNR1BMAPK1HIF1A | |
| SCHEMBL8103817 | 0.75 | MTNR1A (0.67) | KDM4EMTNR1AMTNR1BMAPK1HIF1A | |
| SCHEMBL9453929 | 0.74 | CYSLTR2 (0.61) | LTB4RFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044541-B1 | AMINOCARBOXYLIC ACIDS, AMINO ALCOHOLS, OR THE DERIVATIVES THEREOF, PROCESSES FOR PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITION, CONTAINING AT LEAST ONE OF THESE COMPOUNDS | TEIJIN LIMITED (JP) | 1983-09-21 | — | — | EP | disclosed |
| EP-0044541-A1 | Aminocarboxylic acids, amino alcohols, or the derivatives thereof, processes for production thereof, and pharmaceutical composition, containing at least one of these compounds | TEIJIN LIMITED (JP) | 1982-01-27 | — | — | EP | disclosed |