Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | HRH1 | P35367 | 4/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11132219 | 1.00 | MAOA (0.58) | MAOAHRH1CA2HTR2ACYP4A11 | |
| SCHEMBL25943080 | 0.91 | MAOA (0.54) | MAOAHRH1CA2HTR2ACYP4A11 | |
| SCHEMBL2361398 | 0.88 | MAOA (0.60) | MAOAHRH1CA2HTR2AKDM4E | |
| SCHEMBL9350714 | 0.88 | MAOA (0.71) | MAOAHRH1CA2HTR2A | |
| SCHEMBL1049854 | 0.86 | HTR2A (0.60) | CA2HTR2ACYP4A11KDM4EALDH1A1 | |
| SCHEMBL3680378 | 0.85 | MAOA (0.75) | MAOAHRH1HTR2AKDM4EALDH1A1 | |
| SCHEMBL10451946 | 0.84 | HTR2A (0.59) | MAOACA2HTR2ACYP4A11CYP4F2 | |
| SCHEMBL2325226 | 0.84 | MAOA (0.60) | MAOAHRH1CA2HTR2AKDM4E | |
| SCHEMBL23837668 | 0.83 | CA2 (0.63) | CA2HTR2ACYP4A11LTA4HEPHX2 | |
| SCHEMBL3424786 | 0.83 | CA2 (0.63) | CA2HTR2ACYP4A11LTA4HEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044541-B1 | AMINOCARBOXYLIC ACIDS, AMINO ALCOHOLS, OR THE DERIVATIVES THEREOF, PROCESSES FOR PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITION, CONTAINING AT LEAST ONE OF THESE COMPOUNDS | TEIJIN LIMITED (JP) | 1983-09-21 | — | — | EP | disclosed |