Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | HRH1 | P35367 | 2/20 | 0.48 |
| ▸ | AKT2 | P31751 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11136805 | 0.91 | MAOA (0.58) | MAOACA2HRH1HTR2ACYP4A11 | |
| SCHEMBL11132219 | 0.91 | MAOA (0.58) | MAOACA2HRH1HTR2ACYP4A11 | |
| SCHEMBL3535251 | 0.87 | CA2 (0.54) | CA2CYP4A11HRH3LTA4HEPHX2 | |
| SCHEMBL2361398 | 0.85 | MAOA (0.60) | MAOACA2HRH1HTR2A | |
| SCHEMBL1049854 | 0.82 | HTR2A (0.60) | CA2HTR2ACYP4A11 | |
| SCHEMBL15870453 | 0.82 | CA2 (0.57) | CA2CYP4A11CYP4F2RARB | |
| SCHEMBL15245000 | 0.82 | AKT2 (0.62) | MAOAHRH1AKT2MAOBHTR2A | |
| SCHEMBL3680378 | 0.82 | MAOA (0.75) | MAOAHRH1MAOBHTR2A | |
| SCHEMBL8911924 | 0.81 | MAOA (0.75) | MAOAHRH1AKT2MAOBHTR2A | |
| SCHEMBL7140170 | 0.81 | GFER (0.54) | MAOACA2MAOBCYP4A11LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146892-A1 | BIPHENYL-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS | PARION SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |