SCHEMBL111369

SCHEMBL111369

CC(C)(C)[Si](C)(C)OCC1CO1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.52
TSHR P16473 5/20 0.48
MAPK1 P28482 1/20 0.48
TP53 P04637 4/20 0.39
MAPT P10636 2/20 0.39
HPGD P15428 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
HIF1A Q16665 2/20 0.39
CYP1A2 P05177 1/20 0.39
PPARG P37231 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
TDP1 Q9NUW8 2/20 0.35
CYP3A4 P08684 2/20 0.34
GLA P06280 1/20 0.33
TOP2A P11388 1/20 0.30
DUT P33316 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL590696 1.00 ALDH1A1 (0.52) ALDH1A1TSHRMAPK1TP53MAPT
SCHEMBL632976 1.00 ALDH1A1 (0.52) ALDH1A1TSHRMAPK1TP53MAPT
SCHEMBL24501644 0.89 ALDH1A1 (0.42) ALDH1A1TSHRMAPK1TP53MAPT
SCHEMBL17193272 0.89 ALDH1A1 (0.42) ALDH1A1TSHRMAPK1TP53MAPT
SCHEMBL14648425 0.84 ALDH1A1 (0.39) ALDH1A1TSHRMAPK1TP53MAPT
SCHEMBL14648427 0.84 ALDH1A1 (0.39) ALDH1A1TSHRMAPK1TP53MAPT
SCHEMBL14648428 0.83 TDP1 (0.41) ALDH1A1TSHRMAPK1TP53MAPT
SCHEMBL14648426 0.83 TDP1 (0.41) ALDH1A1TSHRMAPK1TP53MAPT
SCHEMBL22832976 0.79 ALDH1A1 (0.33) ALDH1A1TSHRMAPK1
SCHEMBL22227901 0.79 ALDH1A1 (0.33) ALDH1A1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 383 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119843179-A SA266Gr.4 forging for nuclear power and manufacturing method thereof 无锡市法兰锻造有限公司 2025-04-18 CN claimed
CN-119708491-A Polydisulfide polymer material containing hydroxy ester group and preparation method thereof 衢州化工新材料创新研究院 2025-03-28 CN claimed
CN-119542410-A Positive electrode material, preparation method thereof, electrochemical device and electronic device 宁德新能源科技有限公司 2025-02-28 CN claimed
CN-118909552-A High-reflection monocrystalline silicon alkali polishing additive, alkali polishing liquid, preparation method and application 浙江奥首材料科技有限公司 2024-11-08 CN claimed
CN-118184691-A Alkylene oxide hydrolysis-resistant stabilizer containing silane structure and preparation method thereof 宁波三邦超细纤维有限公司 2024-06-14 CN claimed
WO-2024120049-A1 PRIMARY ALCOHOL COMPOUND-BASED SELECTIVE FUNCTIONALIZATION MODIFICATION METHOD 华南理工大学 2024-06-13 WO claimed
CN-219539454-U Distillation tower of chiral tert-butyl dimethyl silicon-based glycidyl ether 常州市华人化工有限公司 2023-08-18 CN claimed
WO-2023082230-A1 POLYMER ALLOY, PREPARATION METHOD THEREFOR, AND USE THEREOF 青岛科技大学 2023-05-19 WO claimed
CN-115894890-A Selective functionalized modification method of primary alcohol compound 华南理工大学 2023-04-04 CN claimed
CN-218554094-U Reaction kettle for chiral tert-butyl dimethyl silicon-based glycidyl ether 常州市华人化工有限公司 2023-03-03 CN claimed
US-8921581-B1 Succinic anhydrides from epoxides CORNELL RESEARCH FOUNDATION, INC. (US) 2014-12-30 US claimed
US-8697453-B2 Particles LIFE TECHNOLOGIES AS (NO) 2014-04-15 US claimed
US-20130099151-A1 PARTICLES Life Technologies Corporation (US) 2013-04-25 US claimed
CN-101535380-B Metal coordinating and film-forming materials BASF CORP 2012-11-28 CN claimed
EP-2051075-B1 Use of superparamagnetic crystals to catalyse polymerisation of epoxide monomers INVITROGEN DYNAL AS (NO) 2011-08-03 EP claimed
US-7794837-B2 Covalently immobilized fluorinated carboxylic acid stationary phase for liquid chromatography The United States of America as represented by the Secretary of Commerce, the National Institute of Standards and Technology (US) 2010-09-14 US claimed
US-7772334-B2 Crosslinker of reactive functional groups and nonionic metal coordinating structure-containing alkyl or aromatic compound BASF COATINGS GMBH (DE) 2010-08-10 US claimed
US-7759436-B2 Film-former of resin with nonionic metal coordinating structure and crosslinker-reactive group BASF COATINGS GMBH (DE) 2010-07-20 US claimed
EP-2051075-A1 Particles Invitrogen Dynal AS (NO) 2009-04-22 EP claimed
US-20090043042-A1 Covalently Immobilized Fluorinated Carboxylic Acid Stationary Phase For Liquid Chromatography GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE, 2009-02-12 US claimed