SCHEMBL22832976

SCHEMBL22832976

CC(C)(C)[Si](C)(C)OC[C@@H]1C[C@H](O)CO1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5549512 0.87
SCHEMBL22227901 0.86 ALDH1A1 (0.33) ALDH1A1TSHRMAPK1
SCHEMBL3927317 0.80 TOP2A (0.30)
SCHEMBL590696 0.79 ALDH1A1 (0.52) ALDH1A1TSHRMAPK1
SCHEMBL111369 0.79 ALDH1A1 (0.52) ALDH1A1TSHRMAPK1
SCHEMBL632976 0.79 ALDH1A1 (0.52) ALDH1A1TSHRMAPK1
SCHEMBL24501644 0.77 ALDH1A1 (0.42) ALDH1A1TSHRMAPK1
SCHEMBL17173693 0.75
SCHEMBL9264253 0.74 TOP2A (0.43)
SCHEMBL22555900 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020260857-A1 HYDROXAMATE COMPOUNDS AS ANTAGONISTS OF THE ADENOSINE A2A RECEPTOR AdoRx Therapeutics Limited (GB) 2020-12-30 WO disclosed