Sugi Predict

Sugi Predict / Compounds / SCHEMBL632976

SCHEMBL632976

SCHEMBL632976

CC(C)(C)[Si](C)(C)OC[C@H]1CO1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 8/20 0.52
▸ TSHR P16473 5/20 0.48
▸ MAPK1 P28482 1/20 0.48
▸ TP53 P04637 4/20 0.39
▸ MAPT P10636 2/20 0.39
▸ HPGD P15428 2/20 0.39
▸ MEN1 O00255 2/20 0.39
▸ KMT2A Q03164 2/20 0.39
▸ HIF1A Q16665 2/20 0.39
▸ CYP1A2 P05177 1/20 0.39
▸ PPARG P37231 1/20 0.39
▸ SMN1; SMN2 Q16637 2/20 0.38
▸ TDP1 Q9NUW8 2/20 0.35
▸ CYP3A4 P08684 2/20 0.34
▸ GLA P06280 1/20 0.33
▸ TOP2A P11388 1/20 0.30
▸ DUT P33316 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL111369 1.00 ALDH1A1 (0.52) ALDH1A1TSHRMAPK1TP53MAPT
SCHEMBL590696 1.00 ALDH1A1 (0.52) ALDH1A1TSHRMAPK1TP53MAPT
SCHEMBL24501644 0.89 ALDH1A1 (0.42) ALDH1A1TSHRMAPK1TP53MAPT
SCHEMBL17193272 0.89 ALDH1A1 (0.42) ALDH1A1TSHRMAPK1TP53MAPT
SCHEMBL14648425 0.84 ALDH1A1 (0.39) ALDH1A1TSHRMAPK1TP53MAPT
SCHEMBL14648427 0.84 ALDH1A1 (0.39) ALDH1A1TSHRMAPK1TP53MAPT
SCHEMBL14648428 0.83 TDP1 (0.41) ALDH1A1TSHRMAPK1TP53MAPT
SCHEMBL14648426 0.83 TDP1 (0.41) ALDH1A1TSHRMAPK1TP53MAPT
SCHEMBL22832976 0.79 ALDH1A1 (0.33) ALDH1A1TSHRMAPK1
SCHEMBL22227901 0.79 ALDH1A1 (0.33) ALDH1A1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119709046-A Waterproof starch glue and preparation method and application thereof 浙江华信科技发展有限公司 2025-03-28 — — CN claimed
CN-118308060-B Polyurethane adhesive capable of resisting yellowing and application thereof 广州市奥悦盛体育产业有限公司 2024-11-15 — — CN claimed
CN-118308060-A Polyurethane adhesive capable of resisting yellowing and application thereof 广州市奥悦盛体育产业有限公司 2024-07-09 — — CN claimed
CN-115894890-A Selective functionalized modification method of primary alcohol compound 华南理工大学 2023-04-04 — — CN claimed
CN-115602919-A Electrolyte salt-initiated polysiloxane-based solid polymer electrolyte and application thereof 哈尔滨工业大学（CN） 2023-01-13 — — CN claimed
EP-4631942-A1 PAN-KRAS DEGRADING AGENT, AND PREPARATION METHOD THEREFOR AND USE THEREOF Leadingtac Pharmaceutical (Shaoxing) Co., Ltd. (CN) 2025-10-15 — — EP disclosed
EP-4606803-A1 KRAS G12D DEGRADATION AGENT, AND PREPARATION METHOD AND USE THEREFOR Leadingtac Pharmaceutical (Shaoxing) Co., Ltd. (CN) 2025-08-27 — — EP disclosed
CN-119912901-A Water-triggered adhesive and preparation method and application thereof 北京林业大学 2025-05-02 — — CN disclosed
CN-119709046-A Waterproof starch glue and preparation method and application thereof 浙江华信科技发展有限公司 2025-03-28 — — CN disclosed
CN-118308060-B Polyurethane adhesive capable of resisting yellowing and application thereof 广州市奥悦盛体育产业有限公司 2024-11-15 — — CN disclosed
US-20240351997-A1 NOVEL PARP7 INHIBITOR AND USE THEREOF SHANGHAI QILU PHARMACEUTICAL RESEARCH AND DEVELOPMENT CENTRE LTD. (CN) 2024-10-24 — — US disclosed
CN-118666669-A Efficient asymmetric synthesis method of sitafloxacin intermediate (1S, 2S) -2-fluorocyclopropyl carboxylic acid 四川大学 2024-09-20 — — CN disclosed
US-20020055497-A1 Method for treating allergies using substituted pyrazoles BUTLER CHRISTOPHER R (US) 2002-05-09 — — US disclosed
WO-2002020011-A2 A METHOD FOR TREATING ALLERGIES USING SUBSTITUTED PYRAZOLES ORTHO MCNEIL PHARMACEUTICAL, INC. (US) 2002-03-14 — — WO disclosed
WO-2002014315-A2 SUBSTITUTED PYRAZOLES ORTHO MCNEIL PHARMACEUTICAL, INC. (US) 2002-02-21 — — WO disclosed
US-5459271-A Arylbicyclooctanes as inhibitors of leukotriene biosynthesis MERCK FROSST CANADA, INC. (CA) 1995-10-17 — — US disclosed
US-5428060-A Useful as antiasthamatic, antiallergic, antiinflammatory and cytoprotective agent MERCK FROSST CANADA, INC. (CA) 1995-06-27 — — US disclosed
WO-1995003309-A1 ARYLBICYCLOOCTANES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS MERCK FROSST CANADA INC. (CA) 1995-02-02 — — WO disclosed
WO-1994005657-A1 HETEROARYLNAPHTHALENE HYDROXY ACIDS AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS MERCK FROSST CANADA INC. (CA) 1994-03-17 — — WO disclosed
US-5252599-A Antiasthma, antiallergens, antiinflammatory agents MERCK FROSST CANADA, INC. (CA) 1993-10-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020055497-A1 Method for treating allergies using substituted pyrazoles TSLP, IL33, HRH2 ALDH1A1 1241/4885TSHR 3003/4885MAPK1 4370/4885
US-20240351997-A1 NOVEL PARP7 INHIBITOR AND USE THEREOF PARP6, PARP4, PARP3 ALDH1A1 549/4885TSHR 4789/4885MAPK1 470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.