Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11136415 | 0.92 | GAA (0.43) | GAAMAPK1PTPN7DUSP3PTPN5 | |
| SCHEMBL11659898 | 0.87 | HTT (0.37) | GAATAAR1EGFRERBB2HTT | |
| SCHEMBL11136950 | 0.87 | GAA (0.44) | GAAMAPK1PTPN7DUSP3PTPN5 | |
| SCHEMBL11141205 | 0.86 | ALDH1A1 (0.44) | GAAMAPK1ALDH1A1ATMNPSR1 | |
| SCHEMBL11272026 | 0.85 | CACNA1C (0.44) | EGFRNPSR1HTTLMNA | |
| SCHEMBL11839275 | 0.84 | HTT (0.36) | TAAR1EGFRERBB2HTTMEN1 | |
| SCHEMBL11055529 | 0.83 | HTT (0.40) | GAAALDH1A1HTTMEN1LMNA | |
| SCHEMBL11835524 | 0.82 | LIPG (0.38) | HTTMEN1KMT2A | |
| SCHEMBL11844367 | 0.82 | LIPG (0.38) | HTTMEN1KMT2A | |
| SCHEMBL11074940 | 0.81 | GAA (0.50) | GAAMAPK1PTPN7DUSP3PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4418209-A | ANTIULCER, ANTIARRYTHMIC, ANTIDIARRHEAL, ANTISPASMODIC, ANTIPARASITIC, AND ANTISECRETORY AGENTS | WILLIAM H. RORER, INC. (US) | 1983-11-29 | — | — | US | disclosed |