Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | BID | P55957 | 3/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.36 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.36 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11835524 | 1.00 | LIPG (0.38) | LIPGBIDMCL1PPARABCL2L1 | |
| SCHEMBL11839275 | 0.99 | HTT (0.36) | LIPGBIDMCL1PPARABCL2L1 | |
| SCHEMBL11659898 | 0.95 | HTT (0.37) | LIPGHTTALOX5PTGS2MEN1 | |
| SCHEMBL11660957 | 0.90 | TAAR1 (0.35) | HTTPTGS2SMN1; SMN2CYP3A4 | |
| SCHEMBL11661761 | 0.84 | CACNA1C (0.43) | HTTPTGS2SMN1; SMN2ALOX15TSHR | |
| Hydrochloric Acid SCHEMBL11836746 | 0.83 | CACNA1C (0.43) | HTTPTGS2SMN1; SMN2ALOX15TSHR | |
| SCHEMBL11272026 | 0.82 | CACNA1C (0.44) | BIDMCL1BCL2L1BAK1HTT | |
| SCHEMBL11137128 | 0.82 | GAA (0.41) | HTTMEN1KMT2A | |
| SCHEMBL11659893 | 0.82 | CACNA1C (0.45) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL11661996 | 0.81 | MEN1 (0.38) | HTTMEN1KMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959488-A | 1-Substituted biguanides for treating hyperacidity or ulceration | WILLIAM H. RORER, INC. (US) | 1976-05-25 | — | — | US | disclosed |