Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 11/20 | 0.55 |
| ▸ | IDO1 | P14902 | 2/20 | 0.54 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.48 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.48 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.48 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11135151 | 0.99 | KMO (0.56) | KMOIDO1CDYL2CDYLCDY1; CDY1B | |
| SCHEMBL11138216 | 0.89 | IDO1 (0.54) | KMOIDO1CDYL2CDYLCDY1; CDY1B | |
| SCHEMBL11135042 | 0.86 | IDO1 (0.51) | KMOIDO1CDYL2CDYLCDY1; CDY1B | |
| SCHEMBL5423077 | 0.82 | IDO1 (0.62) | KMOIDO1CDYL2CDYLCDY1; CDY1B | |
| SCHEMBL11133037 | 0.81 | KMO (0.79) | KMOIDO1 | |
| SCHEMBL2061822 | 0.81 | IDO1 (0.64) | KMOIDO1CDYL2CDYLCDY1; CDY1B | |
| SCHEMBL11134988 | 0.80 | KMO (0.81) | KMOIDO1 | |
| SCHEMBL11239672 | 0.80 | KMO (0.57) | KMOAPEX1ALDH1A1NPSR1 | |
| SCHEMBL11137490 | 0.78 | ALDH1A1 (0.75) | ALDH1A1NPSR1 | |
| SCHEMBL11135285 | 0.78 | ALDH1A1 (0.75) | ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4377695-A | ANTIINFLAMMATORY, ANALGESIC, ANTICOAGULANT AGENTS | A. NATTERMANN & CIE GMBH (DE) | 1983-03-22 | — | — | US | disclosed |
| EP-0051827-A1 | Omega-(2-oxo-benzimidazolinyl)-alkanoic acid derivatives, process for producing the same and pharmaceutical compounds containing the same | A. Nattermann & Cie. GmbH (DE) | 1982-05-19 | — | — | EP | disclosed |