Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 15/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11137793 | 0.85 | KMO (0.50) | KMOALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL11134988 | 0.85 | KMO (0.81) | KMO | |
| SCHEMBL11133037 | 0.84 | KMO (0.79) | KMO | |
| SCHEMBL11135147 | 0.81 | ALDH1A1 (0.77) | ALDH1A1NPSR1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL11139506 | 0.81 | ALDH1A1 (0.77) | ALDH1A1NPSR1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL11135151 | 0.81 | KMO (0.56) | KMOALDH1A1NPSR1APEX1 | |
| SCHEMBL11137490 | 0.80 | ALDH1A1 (0.75) | ALDH1A1NPSR1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL11135285 | 0.80 | ALDH1A1 (0.75) | ALDH1A1NPSR1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL11138199 | 0.80 | KMO (0.55) | KMOALDH1A1NPSR1APEX1 | |
| SCHEMBL11136597 | 0.77 | MIF (0.55) | KMOALDH1A1NPSR1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051827-A1 | Omega-(2-oxo-benzimidazolinyl)-alkanoic acid derivatives, process for producing the same and pharmaceutical compounds containing the same | A. Nattermann & Cie. GmbH (DE) | 1982-05-19 | — | — | EP | claimed |