Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 2/20 | 0.31 |
| ▸ | PLAT | P00750 | 2/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | CD38 | P28907 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11138235 | 1.00 | CA2 (0.37) | CA2P2RX1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL11151747 | 0.80 | CA2 (0.39) | CA2GABRA1GABRB2ALOX12TSHR | |
| SCHEMBL11151748 | 0.80 | CA2 (0.39) | CA2GABRA1GABRB2ALOX12TSHR | |
| SCHEMBL9892427 | 0.73 | CA2 (0.70) | CA2GABRA1GABRB2ALOX12HSP90AA1 | |
| SCHEMBL11145354 | 0.70 | CA2 (0.36) | CA2P2RX1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL8387507 | 0.70 | CA2 (0.46) | CA2GABRA1GABRB2KLKB1ALOX12 | |
| SCHEMBL11143059 | 0.69 | ALDH1A1 (0.50) | CA2TSHR | |
| SCHEMBL11143057 | 0.69 | ALDH1A1 (0.50) | CA2TSHR | |
| SCHEMBL30779693 | 0.67 | KLKB1 (0.51) | P2RX1P2RX4P2RX7TMPRSS4KLKB1 | |
| SCHEMBL27588848 | 0.67 | KLKB1 (0.40) | P2RX1P2RX4P2RX7TMPRSS4KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4418220-A | Novel indene compound and novel process for producing indene compounds | MITSUI TOATSU CHEMICALS INC. (JP) | 1983-11-29 | — | — | US | disclosed |
| US-4366328-A | HEAT DECOMPOSITION OF A 1,1,3-TRIMETHYL, 3-HYDROXYPHENYL, HYDROXYINDANE USING AN ACID OR BASIC CATALYST; DEARYLATION; AROMATIZATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1982-12-28 | — | — | US | disclosed |