Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11151747 | 1.00 | CA2 (0.39) | CA2ALDH1A1TDP1TSHRLMNA | |
| SCHEMBL11138235 | 0.80 | CA2 (0.37) | CA2TSHRGABRA1GABRB2ALOX12 | |
| SCHEMBL11138233 | 0.80 | CA2 (0.37) | CA2TSHRGABRA1GABRB2ALOX12 | |
| SCHEMBL11143057 | 0.79 | ALDH1A1 (0.50) | CA2ALDH1A1TDP1TSHRLMNA | |
| SCHEMBL11143059 | 0.79 | ALDH1A1 (0.50) | CA2ALDH1A1TDP1TSHRLMNA | |
| SCHEMBL11306335 | 0.73 | CA2 (0.52) | CA2ALDH1A1TDP1TSHRLMNA | |
| SCHEMBL7059289 | 0.71 | ALDH1A1 (0.41) | CA2ALDH1A1TDP1TSHRLMNA | |
| SCHEMBL5587986 | 0.71 | CA2 (0.50) | CA2ALDH1A1TDP1TSHRLMNA | |
| SCHEMBL9495142 | 0.71 | CA2 (0.54) | CA2ALDH1A1TDP1TSHRLMNA | |
| SCHEMBL36109 | 0.71 | CA2 (0.76) | CA2ALDH1A1TDP1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4418220-A | Novel indene compound and novel process for producing indene compounds | MITSUI TOATSU CHEMICALS INC. (JP) | 1983-11-29 | — | — | US | disclosed |
| US-4366328-A | HEAT DECOMPOSITION OF A 1,1,3-TRIMETHYL, 3-HYDROXYPHENYL, HYDROXYINDANE USING AN ACID OR BASIC CATALYST; DEARYLATION; AROMATIZATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1982-12-28 | — | — | US | disclosed |