Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13341488 | 1.00 | THRA (0.51) | THRATHRBESR1HTTL3MBTL1 | |
| SCHEMBL6232233 | 0.92 | THRA (0.43) | THRATHRBESR1HTTL3MBTL1 | |
| SCHEMBL11428493 | 0.91 | THRA (0.46) | THRATHRBTLR8MEN1NR1I2 | |
| SCHEMBL8956169 | 0.90 | ALOX15 (0.54) | THRATHRBESR1LMNACYP3A4 | |
| SCHEMBL11419539 | 0.90 | ALOX15 (0.54) | THRATHRBESR1LMNACYP3A4 | |
| SCHEMBL8956466 | 0.86 | THRA (0.48) | THRATHRBESR1LMNACYP3A4 | |
| SCHEMBL21689793 | 0.85 | PTGS1 (0.41) | THRATHRBHTTL3MBTL1TLR8 | |
| SCHEMBL5847066 | 0.85 | MAPT (0.45) | THRATHRBESR1HTTTLR8 | |
| SCHEMBL12433812 | 0.84 | THRA (0.55) | THRATHRBHTTLMNA | |
| SCHEMBL12433815 | 0.84 | THRA (0.43) | THRATHRBESR1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4390617-A | GROUP 1A OR 2A PHOSPHATE OR PHOSPHITE AS A BASE GENERATING AGENT | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1983-06-28 | — | — | US | disclosed |