Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11419539 | 1.00 | ALOX15 (0.54) | ALOX15TP53LMNACYP3A4HPGD | |
| SCHEMBL8956466 | 0.94 | THRA (0.48) | ALOX15TP53LMNACYP3A4HPGD | |
| SCHEMBL13341488 | 0.90 | THRA (0.51) | LMNACYP3A4MAPTTHRATHRB | |
| SCHEMBL11138643 | 0.90 | THRA (0.51) | LMNACYP3A4MAPTTHRATHRB | |
| Hydrochloric Acid SCHEMBL10780735 | 0.85 | THRA (0.44) | ALOX15TP53LMNACYP3A4HPGD | |
| SCHEMBL10611020 | 0.83 | THRA (0.45) | LMNACYP3A4CYP1A2MAPTTHRA | |
| SCHEMBL6232233 | 0.82 | THRA (0.43) | ALOX15TP53LMNACYP3A4HPGD | |
| SCHEMBL11428493 | 0.82 | THRA (0.46) | LMNACYP3A4ALDH1A1MAPTTHRA | |
| Hydrochloric Acid SCHEMBL9453289 | 0.82 | THRA (0.44) | LMNACYP3A4CYP1A2MAPTTHRA | |
| SCHEMBL8390582 | 0.81 | ALOX15 (0.44) | ALOX15TP53LMNACYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0374513-B1 | Novel bis-arylphosphate ester antagonists of platelet activating factor | AMERICAN CYANAMID CO (US) | 1996-01-10 | — | — | EP | disclosed |
| US-5328901-A | Respiratory system disorders | AMERICAN CYANAMID COMPANY (US) | 1994-07-12 | — | — | US | disclosed |
| US-5231091-A | Antihistamines, anaphylactic, respiratory system disorders, cardiovascular disorders ans septic shock | AMERICAN CYANAMID COMPANY (US) | 1993-07-27 | — | — | US | disclosed |
| US-5147864-A | Bronchodilator agent, antianaphylactic agent, antishock agent, cardiotonic agent and anticarcinogenic agent | AMERICAN CYANAMID COMPANY (US) | 1992-09-15 | — | — | US | disclosed |
| US-4983592-A | Bis-arylphosphate ester antagonists of platelet activating factor | AMERICAN CYANAMID CO. (US) | 1991-01-08 | — | — | US | disclosed |
| EP-0374513-A2 | Novel bis-arylphosphate ester antagonists of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1990-06-27 | — | — | EP | disclosed |