Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 13/20 | 0.54 |
| ▸ | DRD5 | P21918 | 13/20 | 0.54 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 13/20 | 0.52 |
| ▸ | DRD4 | P21917 | 13/20 | 0.52 |
| ▸ | DRD3 | P35462 | 12/20 | 0.52 |
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11254459 | 0.98 | MAOA (0.53) | DRD1DRD5SETD7DRD2DRD4 | |
| SCHEMBL9615962 | 0.92 | SETD7 (0.59) | DRD1DRD5SETD7DRD2DRD4 | |
| SCHEMBL11131856 | 0.85 | MAOA (0.68) | DRD1DRD5SETD7DRD2DRD4 | |
| SCHEMBL7973918 | 0.84 | DRD1 (0.71) | DRD1DRD5DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL11095470 | 0.84 | MAOA (0.69) | DRD1DRD5SETD7DRD2DRD4 | |
| SCHEMBL9518975 | 0.81 | DRD1 (0.52) | DRD1DRD5SETD7DRD2DRD4 | |
| SCHEMBL16404875 | 0.80 | DRD1 (0.49) | DRD1DRD5SETD7DRD2DRD4 | |
| SCHEMBL11099611 | 0.80 | SETD7 (0.47) | DRD1DRD5SETD7DRD2DRD4 | |
| SCHEMBL4500547 | 0.80 | MAOA (0.64) | SETD7MAOAMAOB | |
| SCHEMBL23508952 | 0.79 | DRD1 (0.48) | DRD1DRD5SETD7DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4374133-A | PSYCHOLOGICAL DISORDERS | AKZO N.V. (NL) | 1983-02-15 | — | — | US | disclosed |
| EP-0057777-A1 | Dibenzoxazonine, dibenzoxazecine, dibenzoxaazacycloundecane derivatives and their corresponding thia- and aza derivatives, their preparation and pharmaceutical compositions | AKZO N.V. (NL) | 1982-08-18 | — | — | EP | disclosed |