SCHEMBL7973918

SCHEMBL7973918

CN1CCCc2ccccc2CC1

nearest known ligand 0.71

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DRD1 P21728 17/20 0.71
DRD5 P21918 17/20 0.71
DRD2 P14416 15/20 0.71
DRD3 P35462 15/20 0.71
DRD4 P21917 14/20 0.71
MAOA P21397 2/20 0.71
MAOB P27338 2/20 0.71
TSHR P16473 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL164206 0.90 DRD1 (0.85) DRD1DRD5DRD2DRD3DRD4
SCHEMBL29391320 0.90 DRD1 (0.85) DRD1DRD5DRD2DRD3DRD4
SCHEMBL1950767 0.88 MAOA (0.75) DRD1DRD5DRD2DRD3DRD4
N-Methyl Pyrrolidine (Nmp) SCHEMBL1002256 0.88 DRD1 (0.60) DRD1DRD5DRD2DRD3DRD4
Iodide SCHEMBL12468173 0.87 DRD1 (0.81) DRD1DRD5DRD2DRD3DRD4
Hydrochloric Acid SCHEMBL165521 0.87 MAOA (0.86) DRD1DRD5DRD2DRD3DRD4
SCHEMBL11141355 0.84 DRD1 (0.54) DRD1DRD5DRD2DRD3DRD4
SCHEMBL98108 0.83 MAOA (1.00) DRD1DRD5DRD2DRD3DRD4
SCHEMBL29390912 0.83 MAOA (1.00) DRD1DRD5DRD2DRD3DRD4
Hydrochloric Acid SCHEMBL11254459 0.82 MAOA (0.53) DRD1DRD5DRD2DRD3DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116888127-A Tri-fused ring HPK1 inhibitor and application thereof 轩竹生物科技股份有限公司 2023-10-13 CN disclosed
WO-2023076237-A1 COMPOUNDS AS GLP-1R AGONISTS TERNS PHARMACEUTICALS, INC. (US) 2023-05-04 WO disclosed
WO-2010012812-A1 BENZAZEPINES AND BENZAZOCINES AS SIGMA-RECEPTOR LIGANDES Westfälische Wilhelms Universität Münster (DE) 2010-02-04 WO disclosed