Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11410869 | 0.82 | CYP1A2 (0.54) | LMNAMEN1KMT2ACYP2C9CYP1A2 | |
| SCHEMBL11415296 | 0.82 | CYP1A2 (0.54) | LMNAMEN1KMT2ACYP2C9CYP1A2 | |
| SCHEMBL11415375 | 0.81 | PTGS2 (0.50) | LMNAPTGS2MEN1KMT2ACYP2C9 | |
| SCHEMBL11415378 | 0.81 | PTGS2 (0.50) | LMNAPTGS2MEN1KMT2ACYP2C9 | |
| SCHEMBL11412348 | 0.78 | CA2 (0.51) | LMNAMEN1KMT2ACYP2C9CYP1A2 | |
| SCHEMBL11412346 | 0.78 | CA2 (0.51) | LMNAMEN1KMT2ACYP2C9CYP1A2 | |
| SCHEMBL11415370 | 0.78 | CYP1A2 (0.48) | LMNAMEN1KMT2ACYP2C9CYP1A2 | |
| SCHEMBL11415373 | 0.78 | CYP1A2 (0.48) | LMNAMEN1KMT2ACYP2C9CYP1A2 | |
| SCHEMBL11403832 | 0.74 | PTGS2 (0.53) | LMNAPTGS2CYP2C9CYP1A2SIRT2 | |
| SCHEMBL11403831 | 0.74 | PTGS2 (0.53) | LMNAPTGS2CYP2C9CYP1A2SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4400520-A | Novel process for preparing isoindoline derivatives | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1983-08-23 | — | — | US | disclosed |
| EP-0047674-A1 | Novel process for preparing isoindolin derivatives | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1982-03-17 | — | — | EP | disclosed |