Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | POLA1 | P09884 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11142359 | 0.88 | KDM4E (0.60) | KDM4EPOLA1TAS1R3TAS1R1P2RY1 | |
| SCHEMBL10788490 | 0.86 | KDM4E (0.49) | KDM4EPOLA1TAS1R3TAS1R1P2RY1 | |
| Pyridine SCHEMBL10491050 | 0.84 | KDM4E (0.47) | KDM4EPOLA1TAS1R3TAS1R1P2RY1 | |
| SCHEMBL11281236 | 0.82 | KDM4E (0.46) | KDM4EPOLA1TAS1R3TAS1R1HPGD | |
| SCHEMBL21538044 | 0.82 | KDM4E (0.81) | KDM4EPOLA1TAS1R3TAS1R1POLB | |
| SCHEMBL23225351 | 0.82 | KDM4E (0.77) | KDM4EPOLA1TAS1R3TAS1R1P2RY1 | |
| SCHEMBL31685282 | 0.80 | KDM4E (0.63) | KDM4EPOLA1TAS1R3TAS1R1P2RY1 | |
| SCHEMBL22315215 | 0.80 | KDM4E (0.74) | KDM4EPOLA1TAS1R3TAS1R1P2RY1 | |
| SCHEMBL18166264 | 0.80 | KDM4E (0.74) | KDM4EPOLA1TAS1R3TAS1R1P2RY1 | |
| SCHEMBL9703289 | 0.80 | KDM4E (0.74) | KDM4EPOLA1TAS1R3TAS1R1P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611075-B1 | Modified oligodeoxyribonucleotides, their preparation and their therapeutic use | SANKYO CO (JP) | 1996-12-18 | — | — | EP | disclosed |
| EP-0611075-A1 | Modified oligodeoxyribonucleotides, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-08-17 | — | — | EP | disclosed |