Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11137403 | 0.90 | POLB (0.48) | ALDH1A1ALOX12SMN1; SMN2POLBATM | |
| SCHEMBL11133359 | 0.84 | GAA (0.54) | ALDH1A1ALOX12SMN1; SMN2POLBATM | |
| SCHEMBL9081663 | 0.79 | ALDH1A1 (0.43) | ALDH1A1POLBGAACYP1A2CYP2C19 | |
| SCHEMBL11052356 | 0.79 | POLB (0.51) | ALDH1A1ALOX12SMN1; SMN2POLBATM | |
| SCHEMBL11137110 | 0.77 | CACNA1C (0.51) | ALDH1A1ALOX12SMN1; SMN2GAACYP2C19 | |
| SCHEMBL11665157 | 0.77 | DRD2 (0.40) | ALDH1A1POLBGAACYP1A2CYP2C19 | |
| SCHEMBL11266711 | 0.76 | MAPT (0.41) | ALDH1A1ALOX12SMN1; SMN2POLBATM | |
| SCHEMBL11054397 | 0.76 | LMNA (0.51) | ALDH1A1ALOX12SMN1; SMN2POLBATM | |
| SCHEMBL11133485 | 0.76 | LMNA (0.45) | ALDH1A1ALOX12SMN1; SMN2POLBATM | |
| SCHEMBL11141083 | 0.75 | POLB (0.44) | ALDH1A1ALOX12SMN1; SMN2POLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4418209-A | ANTIULCER, ANTIARRYTHMIC, ANTIDIARRHEAL, ANTISPASMODIC, ANTIPARASITIC, AND ANTISECRETORY AGENTS | WILLIAM H. RORER, INC. (US) | 1983-11-29 | — | — | US | disclosed |