SCHEMBL11143370

SCHEMBL11143370

O=P(CCl)(CCl)c1cccc(Cl)c1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.38
ACP3 P15309 1/20 0.37
ALDH1A1 P00352 3/20 0.37
TSHR P16473 1/20 0.37
CHRM5 P08912 1/20 0.36
TAAR1 Q96RJ0 2/20 0.36
PARP1 P09874 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
KCNN4 O15554 1/20 0.35
KCNA5 P22460 1/20 0.35
IDO1 P14902 2/20 0.34
MGLL Q99685 1/20 0.34
MEN1 O00255 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
HTT P42858 1/20 0.34
KMT2A Q03164 1/20 0.34
CYP3A4 P08684 1/20 0.34
AGXT P21549 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8168112 0.78 ALDH1A1 (0.42) PNMTACP3ALDH1A1TSHRCHRM5
SCHEMBL29968234 0.78 ALDH1A1 (0.42) PNMTACP3ALDH1A1TSHRCHRM5
SCHEMBL11103188 0.76 ACP3 (0.44) PNMTACP3ALDH1A1TSHRCHRM5
SCHEMBL11587700 0.75 CFTR (0.46) ALDH1A1TSHRTDP1MEN1LMNA
SCHEMBL11099508 0.74 ALDH1A1 (0.39) PNMTACP3ALDH1A1TSHRCHRM5
SCHEMBL1069498 0.74 ACP3 (0.47) ACP3ALDH1A1TSHRCHRM5PARP1
SCHEMBL916920 0.74 PGK1 (0.53) ACP3ALDH1A1TSHRCHRM5PARP1
SCHEMBL14450166 0.74 ALDH1A1 (0.39) ACP3ALDH1A1TSHRCHRM5PARP1
SCHEMBL28633152 0.74 ALDH1A1 (0.44) PNMTACP3ALDH1A1TSHRCHRM5
SCHEMBL11605110 0.74 HPGD (0.44) ACP3ALDH1A1TSHRCHRM5PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4382898-A Process for the production of aromatic carboxylic acid chlorides BAYER AKTIENGESELLSCHAFT (DE) 1983-05-10 US disclosed