SCHEMBL11587700

SCHEMBL11587700

O=P(CCl)(CCl)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CFTR P13569 1/20 0.46
CA2 P00918 1/20 0.46
CA4 P22748 1/20 0.46
CA5A P35218 1/20 0.46
ALDH1A1 P00352 4/20 0.44
GAA P10253 2/20 0.44
HTT P42858 2/20 0.44
MAPT P10636 2/20 0.44
ALPG P10696 1/20 0.44
ALOX12 P18054 1/20 0.44
NPY1R P25929 1/20 0.44
NPY2R P49146 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
USP2 O75604 1/20 0.43
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
RECQL P46063 1/20 0.41
LMNA P02545 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10876541 0.79 ALDH1A1 (0.56) CFTRCA2CA4CA5AALDH1A1
SCHEMBL6572723 0.77 CFTR (0.44) CFTRCA2CA4CA5AALDH1A1
SCHEMBL11585975 0.77 LMNA (0.40) ALDH1A1HTTMAPTNPSR1MEN1
SCHEMBL11143370 0.75 PNMT (0.38) ALDH1A1HTTMAPTMEN1KMT2A
SCHEMBL778908 0.74 ALDH1A1 (0.52) CFTRCA2CA4CA5AALDH1A1
Methylene Chloride SCHEMBL28537220 0.74 CFTR (0.46) CFTRCA2CA4CA5AALDH1A1
SCHEMBL3010717 0.74 GAA (0.54) CFTRCA2CA4CA5AALDH1A1
SCHEMBL11588800 0.74 CA2 (0.52) CFTRCA2CA4CA5AALDH1A1
Hydrochloric Acid SCHEMBL11781278 0.73 CFTR (0.64) CFTRCA2CA4CA5AALDH1A1
SCHEMBL11175982 0.72 HPGD (0.52) CFTRCA2CA4CA5AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4130411-A DI(HALOMETHYL)ARYL PHOSPHINE OXIDES M&T CHEMICALS INC. (US) 1978-12-19 US disclosed