SCHEMBL111438

SCHEMBL111438

C1CN(CCOCCN2CCOCC2)CCO1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.58
SMN1; SMN2 Q16637 2/20 0.56
KEAP1 Q14145 1/20 0.56
ALDH1A1 P00352 3/20 0.50
KDM4E B2RXH2 2/20 0.50
MAPK1 P28482 2/20 0.48
CYP1A2 P05177 1/20 0.48
CHRM2 P08172 1/20 0.48
CHRM1 P11229 1/20 0.48
HTR2A P28223 1/20 0.48
SCN1A P35498 1/20 0.48
HTR2B P41595 1/20 0.48
KCNH2 Q12809 1/20 0.48
SCN2A Q99250 1/20 0.48
SIGMAR1 Q99720 1/20 0.48
SCN3A Q9NY46 1/20 0.48
HRH3 Q9Y5N1 1/20 0.48
USP2 O75604 1/20 0.47
LMNA P02545 1/20 0.47
HPGD P15428 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7106263 0.97 TSHR (0.61) TSHRSMN1; SMN2KEAP1ALDH1A1KDM4E
SCHEMBL8362022 0.91 TSHR (0.51) TSHRSMN1; SMN2KEAP1ALDH1A1KDM4E
SCHEMBL5293921 0.90 KEAP1 (0.58) TSHRSMN1; SMN2KEAP1ALDH1A1KDM4E
SCHEMBL2635588 0.89 SMN1; SMN2 (0.63) TSHRSMN1; SMN2KEAP1ALDH1A1KDM4E
SCHEMBL18024012 0.89 TSHR (0.50) TSHRSMN1; SMN2KEAP1ALDH1A1KDM4E
SCHEMBL503668 0.89 KDM4E (0.57) TSHRSMN1; SMN2KEAP1ALDH1A1KDM4E
SCHEMBL3305244 0.89 ALDH1A1 (0.54) TSHRSMN1; SMN2KEAP1ALDH1A1KDM4E
SCHEMBL1467966 0.89 TSHR (0.50) TSHRSMN1; SMN2KEAP1ALDH1A1KDM4E
SCHEMBL666207 0.89 TSHR (0.50) TSHRSMN1; SMN2KEAP1ALDH1A1KDM4E
SCHEMBL9812536 0.88 SMN1; SMN2 (0.56) TSHRSMN1; SMN2KEAP1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6140 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118667427-B Antibacterial and ultraviolet-resistant polyurethane coating 晋江市福大科教园区发展中心 2026-05-12 CN claimed
CN-122011388-A Polyimide precursor, preparation method thereof and polyimide precursor composition 深圳先进电子材料国际创新研究院 2026-05-12 CN claimed
US-12600558-B2 Aerosol can configuration Tremco CPG Germany GmbH (DE) 2026-04-14 US claimed
EP-3938414-B1 A TWO-COMPONENT POLYURETHANE OR POLYISOCYANURATE SPRAY FOAM COMPOSITION CONTAINING A HYDROHALOOLEFIN BLOWING AGENT DDP SPECIALTY ELECTRONIC MATERIALS US LLC (US) 2026-04-01 EP claimed
EP-4661058-A1 CLEANING AGENT COMPOSITION AND CLEANING METHOD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-12-10 EP claimed
EP-4655329-A1 CURABLE POTTING MATERIAL FOR AUTOMOTIVE BATTERY PACKS Sika Technology AG (CH) 2025-12-03 EP claimed
EP-2961782-B2 POLYURETHANE FOAM PREMIXES CONTAINING HALOGENATED OLEFIN BLOWING AGENTS AND FOAMS MADE FROM SAME HONEYWELL INT INC (US) 2025-11-26 EP claimed
EP-4638634-A1 DUALLY CURABLE ADHESIVE COMPOSITION Henkel AG & Co. KGaA (DE) 2025-10-29 EP claimed
US-20250313735-A1 Dually Curable Adhesive Composition HENKEL AG & CO. KGAA (DE) 2025-10-09 US claimed
EP-4423039-B1 POLYMER FREE AND LOW ODOR UREASE INHIBITOR FORMULATION WITH IMPROVED STORAGE STABILITY ON UREA BASF SE (DE) 2025-09-17 EP claimed
EP-0264675-B1 MOISTURE CURABLE SEALANT COMPOSITIONS ESSEX SPECIALTY PRODUCTS, INC. (US) 1992-10-14 EP claimed
US-5002047-A Supporting or cushioning body part with pad of open-celled foam impregnated with water curable polyurethane MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-03-26 US claimed
EP-0306327-A2 Orthotic pads and methods MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-03-08 EP claimed
US-4780520-A POLYURETHANE AND DIMORPHOLINODIETHYL ETHER CATALYST ESSEX SPECIALTY PRODUCTS, INC. (US) 1988-10-25 US claimed
US-4758648-A High speed cure sealant ESSEX SPECIALTY PRODUCTS, INC. (US) 1988-07-19 US claimed
US-4742087-A MOISTURE HARDENING HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1988-05-03 US claimed
EP-0264675-A2 Moisture curable sealant compositions ESSEX SPECIALTY PRODUCTS, INC. (US) 1988-04-27 EP claimed
US-4556546-A Bis tertiary amino alkyl derivatives as solvents for acid gas removal from gas streams AIR PRODUCTS AND CHEMICALS, INC. (US) 1985-12-03 US claimed
EP-0124835-A2 BIS tertiary amino alkyl derivatives as solvents for acid gas removal from gas streams AIR PRODUCTS AND CHEMICALS, INC. (US) 1984-11-14 EP claimed
US-3976593-A TRIETHANOLAMINE BISULFITE, CORROSION INHIBITOR PETROLITE CORPORATION (US) 1976-08-24 US claimed