Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | SCN1A | P35498 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL111438 | 0.97 | TSHR (0.58) | TSHRSMN1; SMN2KEAP1ALDH1A1KDM4E | |
| SCHEMBL3299959 | 0.89 | KDM4E (0.55) | TSHRSMN1; SMN2KEAP1ALDH1A1KDM4E | |
| SCHEMBL22840863 | 0.89 | KDM4E (0.55) | TSHRSMN1; SMN2KEAP1ALDH1A1KDM4E | |
| SCHEMBL92600 | 0.89 | TSHR (0.53) | TSHRSMN1; SMN2KEAP1ALDH1A1KDM4E | |
| SCHEMBL3304967 | 0.89 | ALDH1A1 (0.53) | TSHRSMN1; SMN2KEAP1ALDH1A1KDM4E | |
| SCHEMBL501602 | 0.89 | TSHR (0.53) | TSHRSMN1; SMN2KEAP1ALDH1A1KDM4E | |
| SCHEMBL525957 | 0.89 | KDM4E (0.55) | TSHRSMN1; SMN2KEAP1ALDH1A1KDM4E | |
| SCHEMBL11428304 | 0.89 | TSHR (0.53) | TSHRSMN1; SMN2KEAP1ALDH1A1KDM4E | |
| SCHEMBL526235 | 0.89 | TSHR (0.53) | TSHRSMN1; SMN2KEAP1ALDH1A1KDM4E | |
| SCHEMBL25564688 | 0.89 | ALDH1A1 (0.53) | TSHRSMN1; SMN2KEAP1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5455294-A | Water hardenable poly(ether)urethane prepolymer stabilized with maleic anhydride and catalyzed with potassium carbonate and bis(2-morpholinoethoxy)ethane; storage stability | Zhang, Wang Jian (TW) | 1995-10-03 | — | — | US | claimed |
| US-9309271-B2 | Preparation of isocyanato silanes | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2016-04-12 | — | — | US | disclosed |
| US-20150133682-A1 | PREPARATION OF ISOCYANATO SILANES | MOMENTIVE PERFORMANCE MATERIALS INC. | 2015-05-14 | — | — | US | disclosed |
| EP-0775127-B1 | N-ALKYL AMMONIUM ACETONITRILE BLEACH ACTIVATORS | CLOROX CO (US) | 2003-09-17 | — | — | EP | disclosed |
| EP-0968130-A4 | N-ALKYL AMMONIUM ACETONITRILE ACTIVATORS IN DENSE GAS CLEANING AND METHOD | CLOROX CO (US) | 2002-08-14 | — | — | EP | disclosed |
| US-6017464-A | A DIMERIC N-ALKYL AMMONIUM ACETONITRILE COMPOUNDS HAVING SATURATED RINGS THAT INCLUDE QUATERNIZED NITROGEN ATOMS AND TO WHICH CYANO GROUPS ARE BONDED THROUGH A SINGLE CARBON ATOM, AND A SOUCE OF OXYGEN PROVIDES ENHANCED BLEACHING | THE CLOROX COMPANY (US) | 2000-01-25 | — | — | US | disclosed |
| EP-0968130-A1 | N-ALKYL AMMONIUM ACETONITRILE ACTIVATORS IN DENSE GAS CLEANING AND METHOD | The Clorox Company (US) | 2000-01-05 | — | — | EP | disclosed |
| US-5959104-A | N-alkyl ammonium acetonitrile bleach activators | THE CLOROX COMPANY (US) | 1999-09-28 | — | — | US | disclosed |
| US-5958289-A | A QUATERNARY NITROGEN CONTAINING HETEROCYCLIC NITRILE COMPOUND AND A PEROXY COMPOUND | THE CLOROX COMPANY (US) | 1999-09-28 | — | — | US | disclosed |
| US-5877315-A | Dimeric N-Alkyl ammonium acetonitrile bleach activators | THE CLOROX COMPANY (US) | 1999-03-02 | — | — | US | disclosed |
| US-5741437-A | SOURCE OF ACTIVE OXYGEN REACTS WITH NITRILE FOR BLEACHING APPLICATIONS | THE CLOROX COMPANY (US) | 1998-04-21 | — | — | US | disclosed |
| US-5739327-A | OXYGEN BLEACHES OF NITRILE BONDED TO QUATERNARY NITROGEN | THE CLOROX COMPANY (US) | 1998-04-14 | — | — | US | disclosed |
| EP-0775127-A1 | N-ALKYL AMMONIUM ACETONITRILE BLEACH ACTIVATORS | The Clorox Company (US) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996040661-A1 | N-ALKYL AMMONIUM ACETONITRILE BLEACH ACTIVATORS | THE CLOROX COMPANY (US) | 1996-12-19 | — | — | WO | disclosed |
| US-5455294-A | Water hardenable poly(ether)urethane prepolymer stabilized with maleic anhydride and catalyzed with potassium carbonate and bis(2-morpholinoethoxy)ethane; storage stability | Zhang, Wang Jian (TW) | 1995-10-03 | — | — | US | disclosed |
| US-5455294-A | Water hardenable poly(ether)urethane prepolymer stabilized with maleic anhydride and catalyzed with potassium carbonate and bis(2-morpholinoethoxy)ethane; storage stability | Zhang, Wang Jian (TW) | 1995-10-03 | — | — | US | disclosed |
| EP-0214852-B1 | PERFLUOROAMINOETHERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-10-28 | — | — | EP | disclosed |
| US-5049670-A | Pour point | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-09-17 | — | — | US | disclosed |
| US-4929725-A | NONFLAMMABLE, HYDRAULIC FLUIDS | MOORE GEORGE G I (US) | 1990-05-29 | — | — | US | disclosed |
| US-4788339-A | HIGH BOILING, LOW POUR POINT; HYDRAULIC FLUIDS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133682-A1 | PREPARATION OF ISOCYANATO SILANES | CLCN2, CLIC4, CLIC1 | TSHR 4684/4885SMN1; SMN2 3414/4885KEAP1 362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.