SCHEMBL11144597

SCHEMBL11144597

C=CCN1CC1C(=O)OCC

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.36
ALDH1A1 P00352 3/20 0.35
KMT2A Q03164 2/20 0.35
LMNA P02545 1/20 0.35
FKBP1A P62942 2/20 0.35
POLB P06746 1/20 0.35
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11588481 0.80 MAPT (0.40) MAPTALDH1A1KMT2ALMNAFKBP1A
SCHEMBL4730876 0.78 ALDH1A1 (0.40) MAPTALDH1A1KMT2ALMNAFKBP1A
SCHEMBL16133377 0.75 ALDH1A1 (0.47) MAPTALDH1A1KMT2ALMNAFKBP1A
SCHEMBL20077566 0.74 FKBP1A (0.45) ALDH1A1FKBP1A
SCHEMBL27640303 0.74 MEN1 (0.36) MAPTALDH1A1KMT2AMEN1
SCHEMBL11006593 0.73 TSHR (0.36) MAPTALDH1A1KMT2ALMNAFKBP1A
SCHEMBL23420011 0.72 FKBP1A (0.38) MAPTALDH1A1KMT2ALMNAFKBP1A
SCHEMBL9854214 0.72 FKBP1A (0.34) MAPTALDH1A1KMT2ALMNAFKBP1A
SCHEMBL9854219 0.72 FKBP1A (0.34) MAPTALDH1A1KMT2ALMNAFKBP1A
SCHEMBL11147800 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4410532-A N-Substituted aziridine-2-carboxylic acid derivatives and their immuno-stimulation compositions and methods BOEHRINGER MANNHEIM GMBH (DE) 1983-10-18 US disclosed
US-4409236-A N-Substituted aziridine-2-carboxylic acid derivatives and immuno-stimulation composition and method BOEHRINGER MANNHEIM GMBH (DE) 1983-10-11 US disclosed
US-4321194-A N-Substituted aziridine-2-carboxylic acid derivatives for immuno stimulation BOEHRINGER MANNHEIM GMBH (DE) 1982-03-23 US disclosed