Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PPM1B | O75688 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11588481 | 0.86 | MAPT (0.40) | ALDH1A1MAPTKMT2ALMNAFKBP1A | |
| SCHEMBL16133377 | 0.81 | ALDH1A1 (0.47) | ALDH1A1MAPTKMT2ALMNAFKBP1A | |
| SCHEMBL11144597 | 0.78 | MAPT (0.36) | ALDH1A1MAPTKMT2ALMNAFKBP1A | |
| SCHEMBL11147800 | 0.77 | — | — | |
| SCHEMBL11147455 | 0.74 | MEN1 (0.55) | ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL11195762 | 0.73 | FKBP1A (0.42) | ALDH1A1MAPTKMT2ALMNAFKBP1A | |
| SCHEMBL16307662 | 0.72 | ALDH1A1 (0.35) | ALDH1A1MAPTKMT2ALMNAFKBP1A | |
| SCHEMBL11007149 | 0.72 | MAPT (0.39) | ALDH1A1MAPTKMT2ALMNAFKBP1A | |
| SCHEMBL11003797 | 0.72 | MAPT (0.39) | ALDH1A1MAPTKMT2ALMNAFKBP1A | |
| SCHEMBL5373647 | 0.71 | MAPT (0.51) | ALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008046232-A1 | AZIRIDINE ALDEHYDES, AZIRIDINE-CONJUGATED AMINO DERIVATIVES, AZIRIDINE-CONJUGATED BIOMOLECULES AND PROCESSES FOR THEIR PREPARATION | YUDIN ANDREI K (CA) | 2008-04-24 | — | — | WO | disclosed |