Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO2A1 | Q92959 | 1/20 | 0.42 |
| ▸ | PTGFR | P43088 | 5/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11748741 | 0.92 | SLCO2A1 (0.41) | SLCO2A1PTGFRPTGER1PTGER2PTGER3 | |
| SCHEMBL11613919 | 0.92 | SLCO2A1 (0.41) | SLCO2A1PTGFRPTGER1PTGER2PTGER3 | |
| SCHEMBL11607164 | 0.84 | CHRNA7 (0.38) | TBXAS1 | |
| SCHEMBL11608299 | 0.84 | CHRNA7 (0.38) | TBXAS1 | |
| SCHEMBL11721380 | 0.82 | TBXAS1 (0.39) | SLCO2A1PTGFRPTGER1PTGER2PTGER3 | |
| SCHEMBL11545149 | 0.82 | NPC1 (0.37) | PTGFRPTGER1PTGER2PTGER3SMN1; SMN2 | |
| SCHEMBL11549007 | 0.82 | ALDH1A1 (0.36) | SLCO2A1PTGFRPTGER1PTGER3MAPT | |
| SCHEMBL11546964 | 0.82 | NPC1 (0.37) | PTGFRPTGER1PTGER2PTGER3SMN1; SMN2 | |
| SCHEMBL11147899 | 0.80 | RAB9A (0.42) | SMN1; SMN2TBXAS1KDM4E | |
| SCHEMBL11146633 | 0.80 | RAB9A (0.42) | SMN1; SMN2TBXAS1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4404372-A | 15-Substituted-ω-pentanorprostaglandin derivatives | PFIZER INC. (US) | 1983-09-13 | — | — | US | disclosed |
| EP-0084033-A1 | N-PHENYLPYRAZOLE DERIVATIVES. | MAY & BAKER LTD (GB) | 1983-07-27 | — | — | EP | disclosed |
| WO-1983000331-A1 | N-PHENYLPYRAZOLE DERIVATIVES | MAY & BAKER LTD (GB) | 1983-02-03 | — | — | WO | disclosed |
| US-4342868-A | 2-Descarboxy-2-(tetrazol-5-yl)-16,16-dimethyl-17-(2-furyl)-ω-trisnorprostaglandin E2 | PFIZER INC. (US) | 1982-08-03 | — | — | US | disclosed |