Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | CASP3 | P42574 | 2/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11208437 | 0.98 | LMNA (0.52) | LMNAF2TSHRKMT2AALDH1A1 | |
| SCHEMBL674618 | 0.83 | GAA (0.41) | LMNAF2TSHRKMT2AALDH1A1 | |
| SCHEMBL11146578 | 0.80 | AKR1C3 (0.52) | LMNAF2TSHRKMT2AALDH1A1 | |
| SCHEMBL13431310 | 0.78 | NPC1 (0.51) | LMNAF2TSHRKMT2AALDH1A1 | |
| Benzene SCHEMBL27793442 | 0.78 | LMNA (0.70) | LMNAF2TSHRKMT2AALDH1A1 | |
| Hydrogen Peroxide SCHEMBL27952375 | 0.78 | LMNA (0.70) | LMNAF2TSHRKMT2AALDH1A1 | |
| SCHEMBL52413 | 0.78 | LMNA (0.70) | LMNAF2TSHRKMT2AALDH1A1 | |
| SCHEMBL30293518 | 0.76 | CYP2C19 (0.52) | LMNAF2TSHRKMT2AALDH1A1 | |
| SCHEMBL2532512 | 0.76 | TSHR (0.52) | LMNAF2TSHRKMT2AALDH1A1 | |
| SCHEMBL20797071 | 0.76 | LMNA (0.50) | LMNAF2TSHRKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4374938-A | HYDROXIMIC ACID DERIVATIVE AS FREE RADICAL INITIATOR | AKZONA INCORPORATED (US) | 1983-02-22 | — | — | US | disclosed |
| US-4347342-A | Process for initiating radical reactions employing hydroximic acid derivatives | AKZONA INCORPORATED (US) | 1982-08-31 | — | — | US | disclosed |