SCHEMBL11208437

SCHEMBL11208437

O=C(OC(=NO)c1ccccc1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.52
F2 P00734 1/20 0.52
TSHR P16473 4/20 0.48
KMT2A Q03164 5/20 0.46
ALDH1A1 P00352 5/20 0.46
CASP3 P42574 2/20 0.46
SENP7 Q9BQF6 2/20 0.46
SENP6 Q9GZR1 2/20 0.46
PKM P14618 1/20 0.46
TDP1 Q9NUW8 3/20 0.44
TP53 P04637 1/20 0.44
GAA P10253 1/20 0.44
CYP2C19 P33261 1/20 0.44
PLA2G7 Q13093 1/20 0.43
MAPT P10636 4/20 0.42
MAPK1 P28482 1/20 0.42
HIF1A Q16665 1/20 0.42
POLB P06746 1/20 0.42
SLC6A2 P23975 1/20 0.42
SLC6A3 Q01959 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11146604 0.98 LMNA (0.50) LMNAF2TSHRKMT2AALDH1A1
SCHEMBL674618 0.84 GAA (0.41) LMNAF2TSHRKMT2AALDH1A1
SCHEMBL11146578 0.82 AKR1C3 (0.52) LMNAF2TSHRKMT2AALDH1A1
SCHEMBL13431310 0.80 NPC1 (0.51) LMNAF2TSHRKMT2AALDH1A1
Hydrogen Peroxide SCHEMBL27952375 0.79 LMNA (0.70) LMNAF2TSHRKMT2AALDH1A1
Benzene SCHEMBL27793442 0.79 LMNA (0.70) LMNAF2TSHRKMT2AALDH1A1
SCHEMBL52413 0.79 LMNA (0.70) LMNAF2TSHRKMT2AALDH1A1
SCHEMBL30293518 0.78 CYP2C19 (0.52) LMNAF2TSHRKMT2AALDH1A1
SCHEMBL2532512 0.78 TSHR (0.52) LMNAF2TSHRKMT2AALDH1A1
SCHEMBL20797071 0.78 LMNA (0.50) LMNAF2TSHRKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0035291-B1 PROCESS FOR CARRYING OUT RADICAL REACTIONS AND SHAPED ARTICLES OF THE REACTION PRODUCT AKZO N.V. (NL) 1983-05-11 EP disclosed