Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | F12 | P00748 | 1/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11208437 | 0.84 | LMNA (0.52) | GAACYP2C19F2PKMLMNA | |
| SCHEMBL11146604 | 0.83 | LMNA (0.50) | GAACYP2C19F2PKMLMNA | |
| SCHEMBL3891716 | 0.83 | LMNA (0.37) | GAACYP2C19ATMLMNATSHR | |
| SCHEMBL8530450 | 0.80 | TSHR (0.48) | GAACYP2C19F2F10F12 | |
| SCHEMBL8530447 | 0.80 | TSHR (0.48) | GAACYP2C19F2F10F12 | |
| SCHEMBL27951978 | 0.77 | NPSR1 (0.45) | GAALMNATSHRALDH1A1KMT2A | |
| SCHEMBL6920338 | 0.75 | MEN1 (0.44) | GAAATMLMNATSHRALDH1A1 | |
| SCHEMBL10361994 | 0.75 | GAA (0.44) | GAACYP2C19F2F10F12 | |
| SCHEMBL28863986 | 0.73 | TDP1 (0.55) | LMNATSHRALDH1A1HPGDKMT2A | |
| SCHEMBL9710233 | 0.71 | PLA2G7 (0.61) | LMNAKMT2AL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067337-B2 | Agricultural chemical composition | KUMIAI CHEMICAL INDUSTRY CO., LTD (JP) | 2011-11-29 | — | — | US | disclosed |
| US-20090105078-A1 | Agricultural chemical composition | KUMIAI CHEMICAL INDUSTRY CO., LTD (JP) | 2009-04-23 | — | — | US | disclosed |
| EP-1776863-A1 | AGRICULTURAL CHEMICAL COMPOSITION | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-04-25 | — | — | EP | disclosed |
| US-RE37438-E1 | Acetamidine derivatives and their use as inhibitors for the nitric oxide synthase | GLAXO WELLCOME INC. | 2001-11-06 | — | — | US | disclosed |
| US-5866612-A | Acetamidine derivatives and their use as inhibitors for the nitric oxide synthase | GLAXO WELLCOME INC. (US) | 1999-02-02 | — | — | US | disclosed |
| EP-0799191-A1 | ACETAMIDINE DERIVATIVES AND THEIR USE AS INHIBITORS FOR THE NITRIC OXIDE SYNTHASE | THE WELLCOME FOUNDATION LIMITED (GB) | 1997-10-08 | — | — | EP | disclosed |
| WO-1996019440-A1 | ACETAMIDINE DERIVATIVES AND THEIR USE AS INHIBITORS FOR THE NITRIC OXIDE SYNTHASE | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-06-27 | — | — | WO | disclosed |
| US-5215570-A | Plant safening agents | CIBA-GEIGY CORPORATION (US) | 1993-06-01 | — | — | US | disclosed |
| US-5175289-A | Antidotes for protecting cultivated plants from the phytotoxic action of herbicides | CIBA-GEIGY CORPORATION (US) | 1992-12-29 | — | — | US | disclosed |
| US-5041157-A | Protecting soybeans or cereals | CIBA-GEIGY CORPORATION (US) | 1991-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105078-A1 | Agricultural chemical composition | PDXK, DDT, SYMPK | GAA 652/4885CYP2C19 206/4885F2 3546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.