Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11144383 | 0.79 | KDR (0.37) | LIMK1 | |
| SCHEMBL11146665 | 0.77 | MAPT (0.38) | LIMK1 | |
| SCHEMBL11144388 | 0.75 | MEN1 (0.40) | GPR35LIMK1 | |
| SCHEMBL11149355 | 0.74 | LIMK1 (0.45) | LIMK1 | |
| SCHEMBL11548496 | 0.65 | CYP19A1 (0.38) | — | |
| SCHEMBL11156297 | 0.65 | PRMT5 (0.36) | — | |
| SCHEMBL3885414 | 0.62 | GPR35 (0.48) | GPR35 | |
| SCHEMBL14786196 | 0.61 | IKBKB (0.52) | LIMK1 | |
| SCHEMBL25782248 | 0.59 | GPR35 (0.39) | GPR35 | |
| SCHEMBL25782257 | 0.58 | ALDH1A1 (0.51) | GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005357-B1 | N-(BENZOTHIENOPYRAZOL)-AMIDES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-02-09 | — | — | EP | disclosed |
| EP-0005357-A1 | N-(Benzothienopyrazol)-amides and pharmaceutical compositions containing them | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-11-14 | — | — | EP | disclosed |
| US-4140785-A | N-(benzothienopyrazol)amide antirhinoviral agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-02-20 | — | — | US | disclosed |