Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | CASP1 | P29466 | 4/20 | 0.49 |
| ▸ | CASP7 | P55210 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11158332 | 0.84 | PABPC1 (0.43) | MEN1KMT2ACASP1CASP7HSD17B10 | |
| SCHEMBL11149542 | 0.83 | PARP14 (0.47) | MEN1KMT2ACASP1CASP7HSD17B10 | |
| SCHEMBL11144388 | 0.82 | MEN1 (0.40) | MEN1KMT2ACASP1CASP7HSD17B10 | |
| SCHEMBL11146665 | 0.74 | MAPT (0.38) | HSD17B10MAPTKDM4ELMNAALDH1A1 | |
| SCHEMBL11150491 | 0.74 | HSD17B10 (0.41) | MEN1KMT2ACASP1CASP7HSD17B10 | |
| SCHEMBL11344205 | 0.72 | TP53 (0.41) | MEN1KMT2ACASP1CASP7HSD17B10 | |
| SCHEMBL11145759 | 0.71 | RAB9A (0.36) | MEN1KMT2ACASP1CASP7HSD17B10 | |
| SCHEMBL11216887 | 0.70 | ALDH1A1 (0.48) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL11153753 | 0.70 | MAPT (0.43) | MEN1KMT2ACASP1CASP7HSD17B10 | |
| SCHEMBL16273208 | 0.68 | ALDH1A1 (0.44) | MEN1KMT2AMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005357-B1 | N-(BENZOTHIENOPYRAZOL)-AMIDES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-02-09 | — | — | EP | disclosed |
| EP-0005357-A1 | N-(Benzothienopyrazol)-amides and pharmaceutical compositions containing them | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-11-14 | — | — | EP | disclosed |
| US-4140785-A | N-(benzothienopyrazol)amide antirhinoviral agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-02-20 | — | — | US | disclosed |