Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11146991 | 0.78 | CNOT7 (0.46) | ALDH1A1MEN1KMT2APKMKDM4E | |
| SCHEMBL6944407 | 0.75 | HDAC6 (0.50) | ALDH1A1KDM4EHSD17B10LMNASLC2A1 | |
| SCHEMBL13075103 | 0.72 | HDAC3 (0.54) | ALDH1A1MEN1KMT2APKMKDM4E | |
| SCHEMBL6816235 | 0.72 | PNP (0.71) | HSD17B10 | |
| SCHEMBL12724275 | 0.70 | CDK1 (0.47) | ALDH1A1LMNAEP300SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7991717 | 0.70 | ADRA1D (0.48) | ALDH1A1MEN1KMT2APKMKDM4E | |
| SCHEMBL31333089 | 0.70 | ADRA1D (0.51) | ALDH1A1MEN1KMT2APKMKDM4E | |
| SCHEMBL17457945 | 0.69 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2APKMKDM4E | |
| SCHEMBL4313381 | 0.68 | CYP11B1 (0.62) | ALDH1A1MEN1KMT2APKMLMNA | |
| SCHEMBL16483915 | 0.68 | TLR7 (0.61) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4387225-A | Heterocyclic alkylene triazinones | WILLIAM H. RORER, INC. (US) | 1983-06-07 | — | — | US | claimed |
| EP-0078841-A1 | HETEROCYCLIC ALKYLENE TRIAZINONES | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1983-05-18 | — | — | EP | claimed |
| WO-1982004050-A1 | HETEROCYCLIC ALKYLENE TRIAZINONES | RORER INT OVERSEAS (US) | 1982-11-25 | — | — | WO | claimed |