Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | DRD2 | P14416 | 5/20 | 0.63 |
| ▸ | DRD3 | P35462 | 4/20 | 0.63 |
| ▸ | DRD4 | P21917 | 1/20 | 0.59 |
| ▸ | CES1 | P23141 | 2/20 | 0.59 |
| ▸ | BCHE | P06276 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALDH3A1 | P30838 | 4/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.51 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11149873 | 0.93 | DRD2 (0.75) | ALDH1A1TP53DRD2DRD3CES1 | |
| SCHEMBL11148465 | 0.93 | DRD2 (0.71) | ALDH1A1TP53DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL11147710 | 0.91 | DRD2 (0.70) | ALDH1A1TP53DRD2DRD3DRD4 | |
| SCHEMBL11147571 | 0.91 | DRD2 (0.73) | ALDH1A1TP53DRD2DRD3CES1 | |
| Hydrochloric Acid SCHEMBL11153700 | 0.90 | DRD2 (0.72) | ALDH1A1TP53DRD2DRD3CES1 | |
| SCHEMBL31232750 | 0.85 | DRD2 (0.84) | ALDH1A1TP53DRD2DRD3POLB | |
| SCHEMBL9733689 | 0.85 | DRD2 (0.84) | ALDH1A1TP53DRD2DRD3POLB | |
| SCHEMBL11148400 | 0.84 | CES1 (0.51) | ALDH1A1TP53DRD2DRD3CES1 | |
| Hydrochloric Acid SCHEMBL11155882 | 0.83 | CES1 (0.50) | ALDH1A1TP53DRD2DRD3CES1 | |
| Hydrochloric Acid SCHEMBL11146637 | 0.83 | DRD2 (0.56) | ALDH1A1TP53DRD2DRD3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4382934-A | ANTIALLERGENS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-05-10 | — | — | US | disclosed |
| EP-0010398-B1 | ISATIN DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-04-27 | — | — | EP | disclosed |
| EP-0010398-A1 | Isatin derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-04-30 | — | — | EP | disclosed |