Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.73 |
| ▸ | DRD3 | P35462 | 4/20 | 0.73 |
| ▸ | CES1 | P23141 | 2/20 | 0.55 |
| ▸ | CDC25A | P30304 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.53 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11153700 | 0.99 | DRD2 (0.72) | DRD2DRD3CES1CDC25AALDH1A1 | |
| SCHEMBL11149873 | 0.99 | DRD2 (0.75) | DRD2DRD3CES1CDC25AALDH1A1 | |
| SCHEMBL11148465 | 0.96 | DRD2 (0.71) | DRD2DRD3CES1ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL11147710 | 0.95 | DRD2 (0.70) | DRD2DRD3CES1ALDH1A1TP53 | |
| SCHEMBL11147149 | 0.91 | ALDH1A1 (0.65) | DRD2DRD3CES1ALDH1A1TP53 | |
| SCHEMBL11147296 | 0.85 | DRD2 (0.63) | DRD2DRD3ALDH1A1MAOBADRA1B | |
| SCHEMBL11154465 | 0.85 | DRD2 (0.63) | DRD2DRD3ADRA1BP2RX7 | |
| SCHEMBL11151708 | 0.85 | DRD2 (0.63) | DRD2DRD3ALDH1A1MAOBALDH2 | |
| SCHEMBL9256633 | 0.85 | DRD2 (1.00) | DRD2DRD3ALDH1A1MAOB | |
| SCHEMBL11149249 | 0.83 | DRD2 (0.65) | DRD2DRD3ALDH1A1ALDH2ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4382934-A | ANTIALLERGENS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-05-10 | — | — | US | claimed |
| EP-0010398-B1 | ISATIN DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-04-27 | — | — | EP | claimed |
| EP-0010398-A1 | Isatin derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-04-30 | — | — | EP | claimed |
| US-4382934-A | ANTIALLERGENS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-05-10 | — | — | US | disclosed |
| EP-0010398-B1 | ISATIN DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-04-27 | — | — | EP | disclosed |
| EP-0010398-A1 | Isatin derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-04-30 | — | — | EP | disclosed |