Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | RCE1 | Q9Y256 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.49 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16045157 | 0.95 | ALDH1A1 (0.67) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL3020410 | 0.85 | CES1 (0.67) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL28205978 | 0.85 | ALDH1A1 (0.68) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL11147994 | 0.84 | ALDH1A1 (0.62) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL11149576 | 0.84 | ALDH1A1 (0.71) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL29011247 | 0.82 | ALDH1A1 (0.60) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL29011259 | 0.82 | ALDH3A1 (0.60) | ALDH1A1ALDH2ALDH3A1BCHECES1 | |
| SCHEMBL11149802 | 0.82 | PARK7 (0.62) | ALDH1A1ALDH2ALDH3A1BCHECES1 | |
| SCHEMBL29011249 | 0.82 | PARK7 (0.63) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL13546141 | 0.81 | ALDH1A1 (0.65) | ALDH1A1MAPTKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4382934-A | ANTIALLERGENS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-05-10 | — | — | US | disclosed |
| EP-0010398-B1 | ISATIN DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-04-27 | — | — | EP | disclosed |
| EP-0010398-A1 | Isatin derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-04-30 | — | — | EP | disclosed |