Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11162588 | 0.89 | MAPT (0.43) | MAPTALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL11063245 | 0.88 | SMN1; SMN2 (0.43) | MAPTALDH1A1HPGDKMT2AMAOB | |
| SCHEMBL11482845 | 0.82 | NR1I2 (0.41) | MAPTALDH1A1HPGDMAOBHSD17B10 | |
| SCHEMBL11169423 | 0.79 | MAPT (0.40) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11153325 | 0.78 | ALDH1A1 (0.51) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11068444 | 0.78 | PTGS2 (0.40) | HDAC1HDAC8HDAC6ALDH1A1KMT2A | |
| SCHEMBL9796690 | 0.76 | GAA (0.36) | ALDH1A1KMT2AALOX15L3MBTL1CYP1A2 | |
| SCHEMBL11064652 | 0.72 | MGAM (0.33) | ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL11064648 | 0.72 | MGAM (0.33) | ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL11148611 | 0.72 | ALOX15 (0.39) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4400523-A | Process for the preparation of styryl-cyclopropanecarboxylic acid esters and new intermediate products for this process | BAYER AKTIENGESELLSCHAFT (DE) | 1983-08-23 | — | — | US | disclosed |
| US-4325873-A | Process for the preparation of styryl-cyclopropanecarboxylic acid esters and intermediate products for this process | BAYER AKTIENGESELLSCHAFT (DE) | 1982-04-20 | — | — | US | disclosed |