Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | IDO1 | P14902 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 11/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8740072 | 0.91 | LMNA (0.67) | LMNAMAPK1CYP1A2CYP2C19HIF1A | |
| SCHEMBL11526940 | 0.83 | IDO1 (0.47) | LMNAMAPK1CYP1A2CYP2C19HIF1A | |
| SCHEMBL302843 | 0.83 | MAPK1 (0.57) | LMNAMAPK1CYP1A2CYP2C19HIF1A | |
| SCHEMBL8777837 | 0.83 | MAPK1 (0.59) | LMNAMAPK1CYP1A2CYP2C19HIF1A | |
| SCHEMBL8951836 | 0.83 | LMNA (0.59) | LMNAMAPK1CYP1A2CYP2C19HIF1A | |
| SCHEMBL11302008 | 0.83 | MAPK1 (0.77) | LMNAMAPK1CYP1A2CYP2C19HIF1A | |
| SCHEMBL11802246 | 0.82 | MAPK1 (0.51) | LMNAMAPK1CYP1A2CYP2C19HIF1A | |
| SCHEMBL11526696 | 0.82 | MAPK1 (0.51) | LMNAMAPK1CYP1A2CYP2C19HIF1A | |
| SCHEMBL124201 | 0.81 | MAPK1 (0.56) | LMNAMAPK1CYP1A2CYP2C19HIF1A | |
| SCHEMBL18984700 | 0.79 | LMNA (0.52) | LMNAMAPK1CYP1A2CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4376077-A | BLUE GREEN COLOR FOR NYLON | SANDOZ LTD. (CH) | 1983-03-08 | — | — | US | disclosed |