SCHEMBL8777837

SCHEMBL8777837

Nc1ccc(NC2CCCCC2)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 3/20 0.59
▸ LMNA P02545 2/20 0.59
▸ CYP1A2 P05177 1/20 0.59
▸ CYP2C19 P33261 1/20 0.59
▸ HIF1A Q16665 1/20 0.59
▸ HSD17B10 Q99714 1/20 0.59
▸ ADORA2A P29274 4/20 0.54
▸ CSNK1A1 P48729 2/20 0.54
▸ CSNK1D P48730 2/20 0.54
▸ CSNK1G1 Q9HCP0 2/20 0.54
▸ MAOA P21397 2/20 0.54
▸ FGR P09769 1/20 0.54
▸ PIM1 P11309 1/20 0.54
▸ DYRK1A Q13627 1/20 0.54
▸ HIPK2 Q9H2X6 1/20 0.54
▸ MAPT P10636 9/20 0.54
▸ GAA P10253 2/20 0.54
▸ KDM4E B2RXH2 2/20 0.54
▸ MEN1 O00255 5/20 0.50
▸ KMT2A Q03164 5/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8740072 0.91 LMNA (0.67) MAPK1LMNACYP1A2CYP2C19HIF1A
SCHEMBL302843 0.83 MAPK1 (0.57) MAPK1LMNACYP1A2CYP2C19HIF1A
SCHEMBL11147656 0.83 LMNA (0.62) MAPK1LMNACYP1A2CYP2C19HIF1A
SCHEMBL8951836 0.83 LMNA (0.59) MAPK1LMNACYP1A2CYP2C19HIF1A
SCHEMBL11703897 0.81 MAPT (0.54) MAPK1LMNACYP1A2CYP2C19HIF1A
SCHEMBL10813232 0.81 CYP1A2 (0.64) MAPK1LMNACYP1A2CYP2C19HIF1A
SCHEMBL124201 0.81 MAPK1 (0.56) MAPK1LMNACYP1A2CYP2C19HIF1A
SCHEMBL18984700 0.79 LMNA (0.52) MAPK1LMNACYP1A2CYP2C19HIF1A
SCHEMBL10485524 0.79 MAOA (0.50) MAPK1LMNACYP1A2CYP2C19HIF1A
SCHEMBL14134006 0.79 CYP1A2 (0.51) MAPK1LMNACYP1A2CYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 — — US claimed
US-20230139146-A1 DYEING OR LIGHTENING PROCESS USING A HAND-HELD STYLING DEVICE AND A SUBSTRATE L'OREAL (FR) 2023-05-04 — — US disclosed
WO-2018115792-A1 HAIR DYEING METHOD USING ACID DYES COMPRISING A PRETREATMENT USING AN AMINO SILICONE L'OREAL (FR) 2018-06-28 — — WO disclosed
WO-2018115791-A1 HAIR DYEING METHOD USING ACID DYES COMPRISING A PRETREATMENT USING A CATIONIC POLYMER L'OREAL (FR) 2018-06-28 — — WO disclosed
EP-0585873-B1 Method of preparing disazo pigments CLARIANT GMBH (DE) 1997-12-29 — — EP disclosed
US-5559216-A AZO COUPLING HOECHST AG (DE) 1996-09-24 — — US disclosed
US-5493011-A PIGMENTING HIGH MOLECULAR WEIGHT NATURAL OR SYNTHETIC ORGANIC MATERIALS HOECHST AG (DE) 1996-02-20 — — US disclosed
EP-0518909-B1 WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE HOECHST AG (DE) 1994-05-25 — — EP disclosed
EP-0585873-A1 Method of preparing disazo pigments HOECHST AKTIENGESELLSCHAFT (DE) 1994-03-09 — — EP disclosed
EP-0518909-A1 WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE. HOECHST AG (DE) 1992-12-23 — — EP disclosed
US-4309221-A ORGANIC PIGMENTS FOR MACROMOLECULAR SUBSTANCES;GOOD FASTNESS AND HEAT RESISTANCE BAYER AKTIENGESELLSCHAFT (DE) 1982-01-05 — — US disclosed
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 — — US disclosed
US-4284411-A CONDENSATION, PIGMENTING BAYER AKTIENGESELLSCHAFT (DE) 1981-08-18 — — US disclosed
US-4260540-A SPIN DYEING POLYACRYLONITRILE BAYER AKTIENGESELLSCHAFT (DE) 1981-04-07 — — US disclosed
EP-0023617-A1 Anthraquinone-azo compounds, process for their preparation and their use as pigments BAYER AG (DE) 1981-02-11 — — EP disclosed
EP-0023648-A1 Anthraquinone-azomethine compounds, process for their preparation; process for dyeing synthetic fibre materials as well as for pigmenting organic macromolecular materials BAYER AG (DE) 1981-02-11 — — EP disclosed
US-4246401-A Axomethine pigments BAYER AKTIENGESELLSCHAFT (DE) 1981-01-20 — — US disclosed
EP-0022209-A2 Fluor-triazine dyestuffs and their use in dyeing cellulosic fibrous materials BAYER AG (DE) 1981-01-14 — — EP disclosed
EP-0018538-A2 Anthraquinone derivatives, process for their preparation, process for the pigmentation of organic macromolecular materials and pigmented organic macromolecular material BAYER AG (DE) 1980-11-12 — — EP disclosed
US-4225489-A Heterocyclic azo dyes and pigments containing 4-quinazolinone moieties BAYER AKTIENGESELLSCHAFT (DE) 1980-09-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230139146-A1 DYEING OR LIGHTENING PROCESS USING A HAND-HELD STYLING DEVICE AND A SUBSTRATE KRT18, TPM3, PRKDC MAPK1 1636/4885LMNA 1345/4885CYP1A2 488/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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