Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL302843 | 0.91 | MAPK1 (0.57) | LMNAMAPK1CYP1A2CYP2C19HIF1A | |
| SCHEMBL8777837 | 0.91 | MAPK1 (0.59) | LMNAMAPK1CYP1A2CYP2C19HIF1A | |
| SCHEMBL8951836 | 0.91 | LMNA (0.59) | LMNAMAPK1CYP1A2CYP2C19HIF1A | |
| SCHEMBL11147656 | 0.91 | LMNA (0.62) | LMNAMAPK1CYP1A2CYP2C19HIF1A | |
| SCHEMBL124201 | 0.89 | MAPK1 (0.56) | LMNAMAPK1CYP1A2CYP2C19HIF1A | |
| SCHEMBL18984700 | 0.87 | LMNA (0.52) | LMNAMAPK1CYP1A2CYP2C19HIF1A | |
| SCHEMBL124713 | 0.86 | MAPK1 (0.53) | LMNAMAPK1CYP1A2CYP2C19HIF1A | |
| SCHEMBL11302008 | 0.85 | MAPK1 (0.77) | LMNAMAPK1CYP1A2CYP2C19HIF1A | |
| SCHEMBL725855 | 0.85 | MAPK1 (0.53) | LMNAMAPK1CYP1A2CYP2C19HIF1A | |
| SCHEMBL6366530 | 0.84 | MAPK1 (0.51) | LMNAMAPK1CYP1A2CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679808-A | Tertiary non-linear optical material | SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) | 1997-10-21 | — | — | US | claimed |
| US-5679808-A | Tertiary non-linear optical material | SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) | 1997-10-21 | — | — | US | disclosed |
| EP-0635750-A1 | THIRD-ORDER NONLINEAR OPTICAL MATERIAL | SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) | 1995-01-25 | — | — | EP | disclosed |