SCHEMBL11147940

SCHEMBL11147940

CS(=O)(=O)c1nc2ccc(S(=O)(=O)Cl)cc2s1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.49
ALDH1A1 P00352 4/20 0.46
KMT2A Q03164 3/20 0.46
HPGD P15428 2/20 0.46
PKM P14618 2/20 0.46
KDM4E B2RXH2 2/20 0.46
LMNA P02545 1/20 0.46
HSD17B10 Q99714 1/20 0.46
MEN1 O00255 2/20 0.46
CA1 P00915 2/20 0.45
CA4 P22748 2/20 0.45
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
CA5A P35218 2/20 0.44
CA12 O43570 1/20 0.44
CA6 P23280 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
CA5B Q9Y2D0 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11147117 0.88 POLB (0.44) CA2ALDH1A1PKMKDM4ECA1
SCHEMBL11143180 0.85 CA2 (0.49) CA2ALDH1A1KMT2AHPGDPKM
SCHEMBL12821052 0.84 ACP1 (0.50) CA2ALDH1A1KMT2AHPGDPKM
Hydrochloric Acid SCHEMBL11147943 0.83 ACP1 (0.49) CA2ALDH1A1KMT2AHPGDPKM
SCHEMBL609522 0.81 LMNA (0.57) ALDH1A1KMT2AHPGDPKMKDM4E
SCHEMBL11076755 0.81 NPC1 (0.53) CA2ALDH1A1KMT2APKMKDM4E
SCHEMBL11145458 0.81 ALDH1A1 (0.47) CA2ALDH1A1KMT2AHPGDPKM
SCHEMBL14065773 0.79 NPC1 (0.60) CA2ALDH1A1KMT2AHPGDPKM
SCHEMBL1094028 0.79 KMT2A (0.50) CA2ALDH1A1KMT2AHPGDPKM
SCHEMBL9514156 0.78 CA2 (0.47) CA2ALDH1A1KMT2AHPGDPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4398913-A ALKALINE PASTES CASSELLA AKTIENGESELLSCHAFT (DE) 1983-08-16 US disclosed
US-4386935-A Process for producing discharge reserve prints on textile materials with amino-azo-benzene dyes CASSELLA AKTIENGESELLSCHAFT (DE) 1983-06-07 US disclosed