Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 13/20 | 0.64 |
| ▸ | ADRB2 | P07550 | 11/20 | 0.64 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.52 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10898514 | 0.91 | ADRB3 (0.61) | ADRB3ADRB2ADRB1CYP2D6ADRA1D | |
| SCHEMBL9631209 | 0.90 | ADRB3 (0.74) | ADRB3ADRB2ADRB1CYP2D6ADRA1D | |
| SCHEMBL10858066 | 0.90 | ADRB2 (0.51) | ADRB3ADRB2ADRB1CYP2D6ADRA1D | |
| SCHEMBL9799386 | 0.90 | ADRB2 (0.74) | ADRB3ADRB2ADRB1CYP2D6ADRA1D | |
| Hydrochloric Acid SCHEMBL10863169 | 0.89 | ADRB2 (0.50) | ADRB3ADRB2ADRB1CYP2D6ADRA1D | |
| Ethane SCHEMBL11152387 | 0.89 | ADRB3 (0.73) | ADRB3ADRB2ADRB1CYP2D6ADRA1D | |
| SCHEMBL10896428 | 0.85 | ADRB3 (0.55) | ADRB3ADRB2ADRB1CYP2D6ADRA1D | |
| SCHEMBL11245796 | 0.85 | ADRB3 (0.65) | ADRB3ADRB2ADRB1CYP2D6ADRA1D | |
| SCHEMBL10896840 | 0.85 | ADRB2 (0.60) | ADRB3ADRB2ADRB1CYP2D6ADRA1D | |
| SCHEMBL11154189 | 0.84 | ADRB3 (0.74) | ADRB3ADRB2ADRB1CYP2D6ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0070133-A2 | Secondary phenylethanol amines, processes for their preparation and their pharmaceutical application | BEECHAM GROUP PLC (GB) | 1983-01-19 | — | — | EP | disclosed |