Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11146421 | 0.94 | L3MBTL1 (0.45) | L3MBTL1HTTALDH1A1LMNAKMT2A | |
| SCHEMBL11148675 | 0.90 | L3MBTL1 (0.52) | L3MBTL1HTTALDH1A1LMNAKMT2A | |
| SCHEMBL11151463 | 0.89 | L3MBTL1 (0.48) | L3MBTL1HTTALDH1A1LMNANLRP3 | |
| SCHEMBL11148636 | 0.87 | CYP1A2 (0.40) | L3MBTL1HTTALDH1A1LMNAKMT2A | |
| SCHEMBL11146126 | 0.86 | RIPK1 (0.40) | RIPK1ALDH1A1NLRP3KMT2AMAPT | |
| SCHEMBL11141810 | 0.85 | L3MBTL1 (0.45) | L3MBTL1HTTALDH1A1NLRP3KMT2A | |
| SCHEMBL11150764 | 0.84 | L3MBTL1 (0.55) | L3MBTL1HTTALDH1A1LMNAKMT2A | |
| SCHEMBL11151136 | 0.82 | L3MBTL1 (0.42) | L3MBTL1ALDH1A1LMNAKMT2AEGFR | |
| SCHEMBL11000472 | 0.80 | GRM5 (0.39) | RIPK1ALDH1A1LMNANLRP3KMT2A | |
| SCHEMBL11146807 | 0.79 | L3MBTL1 (0.47) | L3MBTL1HTTALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4402964-A | N-Aryl-N'-(3-methyl or ethyl-4-oxothiazolidinylidene)ureas useful for the treatment of epilepsy | MCNEILAB, INC. (US) | 1983-09-06 | — | — | US | disclosed |