Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 3/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | HCK | P08631 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11143127 | 0.93 | L3MBTL1 (0.59) | L3MBTL1LMNAKMT2ASMN1; SMN2EGFR | |
| SCHEMBL11151463 | 0.92 | L3MBTL1 (0.48) | L3MBTL1LMNAKMT2ASMN1; SMN2BLM | |
| SCHEMBL11148694 | 0.88 | L3MBTL1 (0.54) | L3MBTL1LMNAKMT2ASMN1; SMN2EGFR | |
| SCHEMBL11141810 | 0.88 | L3MBTL1 (0.45) | L3MBTL1KMT2ASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL11148675 | 0.86 | L3MBTL1 (0.52) | L3MBTL1LMNAKMT2ASMN1; SMN2EGFR | |
| SCHEMBL11141779 | 0.85 | GRM5 (0.42) | L3MBTL1KMT2AMAPK14SMN1; SMN2GAA | |
| SCHEMBL11144521 | 0.85 | GRM5 (0.42) | L3MBTL1KMT2AMAPK14SMN1; SMN2GAA | |
| SCHEMBL11151136 | 0.85 | L3MBTL1 (0.42) | L3MBTL1LMNAKMT2ASMN1; SMN2BLM | |
| SCHEMBL11148476 | 0.84 | L3MBTL1 (0.42) | L3MBTL1LMNAKMT2ASMN1; SMN2BLM | |
| SCHEMBL11146807 | 0.82 | L3MBTL1 (0.47) | L3MBTL1LMNAKMT2ASMN1; SMN2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4402964-A | N-Aryl-N'-(3-methyl or ethyl-4-oxothiazolidinylidene)ureas useful for the treatment of epilepsy | MCNEILAB, INC. (US) | 1983-09-06 | — | — | US | disclosed |