Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.42 |
| ▸ | ITK | Q08881 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.38 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11146117 | 0.84 | SMN1; SMN2 (0.39) | HDAC6HDAC1SMN1; SMN2RAB9ATP53 | |
| SCHEMBL11267605 | 0.81 | NOD1 (0.38) | NOD1ITKPOLBSMN1; SMN2RAB9A | |
| SCHEMBL11248311 | 0.80 | NOD1 (0.42) | NOD1POLBSMN1; SMN2 | |
| SCHEMBL11256125 | 0.79 | NOD1 (0.42) | NOD1POLBSMN1; SMN2 | |
| SCHEMBL11148341 | 0.75 | NOD1 (0.46) | NOD1POLBSMN1; SMN2 | |
| SCHEMBL11251402 | 0.75 | SMN1; SMN2 (0.49) | NOD1POLBSMN1; SMN2RAB9ATP53 | |
| SCHEMBL11625701 | 0.74 | MAPK14 (0.44) | SMN1; SMN2 | |
| Water SCHEMBL11149536 | 0.74 | MAPK14 (0.44) | SMN1; SMN2 | |
| SCHEMBL11248780 | 0.73 | NOD1 (0.38) | NOD1POLBSMN1; SMN2RAB9A | |
| SCHEMBL11148006 | 0.72 | NOD1 (0.42) | NOD1POLBSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4401817-A | ANTIVIRAL AGENTS | ELI LILLY AND COMPANY (US) | 1983-08-30 | — | — | US | disclosed |
| US-4338329-A | COMBATTING RHINOVIRUSES | ELI LILLY AND COMPANY (US) | 1982-07-06 | — | — | US | disclosed |
| US-4289782-A | PARTICULARLY FOR INHIBITING GROWTH OF RHINOVIRUSES | ELI LILLY AND COMPANY (US) | 1981-09-15 | — | — | US | disclosed |
| US-4230868-A | α-Alkyl-α-hydroxybenzyl-substituted 1-sulfonylbenzimidazoles | ELI LILLY AND COMPANY (US) | 1980-10-28 | — | — | US | disclosed |
| US-4174454-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1979-11-13 | — | — | US | disclosed |
| US-4118742-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1978-10-03 | — | — | US | disclosed |