Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.35 |
| ▸ | MC4R | P32245 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11267605 | 0.92 | NOD1 (0.38) | NOD1NPC1RAB9ASMN1; SMN2STAT1 | |
| SCHEMBL11251402 | 0.89 | SMN1; SMN2 (0.49) | NOD1NPC1RAB9ASMN1; SMN2STAT1 | |
| SCHEMBL11255360 | 0.84 | PI4KB (0.44) | NPC1RAB9ASMN1; SMN2JMJD6HSD17B10 | |
| SCHEMBL11148341 | 0.78 | NOD1 (0.46) | NOD1SMN1; SMN2POLBHSD17B10ALDH1A1 | |
| SCHEMBL11148594 | 0.73 | NOD1 (0.42) | NOD1RAB9ASMN1; SMN2POLB | |
| SCHEMBL11256125 | 0.72 | NOD1 (0.42) | NOD1SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL11151131 | 0.72 | PDE2A (0.45) | NPC1RAB9ASMN1; SMN2STAT1HSD17B10 | |
| SCHEMBL11728750 | 0.70 | MEN1 (0.47) | NOD1NPC1RAB9ASMN1; SMN2JMJD6 | |
| SCHEMBL11621025 | 0.69 | PDE2A (0.48) | NPC1RAB9ASMN1; SMN2STAT1HSD17B10 | |
| SCHEMBL11730587 | 0.69 | PI4KB (0.39) | RAB9ASMN1; SMN2PI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316021-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1982-02-16 | — | — | US | disclosed |
| US-4243813-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1981-01-06 | — | — | US | disclosed |
| US-4196125-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1980-04-01 | — | — | US | disclosed |
| US-4118573-A | ANTIVIRAL AGENTS | ELI LILLY AND COMPANY (US) | 1978-10-03 | — | — | US | disclosed |
| US-4018790-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1977-04-19 | — | — | US | disclosed |