Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ITK | Q08881 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11248780 | 0.92 | NOD1 (0.38) | NOD1ALDH1A1RAB9AJMJD6NPC1 | |
| SCHEMBL11148594 | 0.81 | NOD1 (0.42) | NOD1ITKRAB9ASMN1; SMN2POLB | |
| SCHEMBL11251402 | 0.81 | SMN1; SMN2 (0.49) | NOD1ALDH1A1HPGDKMT2AKDM4E | |
| SCHEMBL11256125 | 0.78 | NOD1 (0.42) | NOD1ALDH1A1KDM4ESMN1; SMN2POLB | |
| SCHEMBL11255360 | 0.76 | PI4KB (0.44) | ALDH1A1KDM4ERAB9AJMJD6NPC1 | |
| SCHEMBL11248311 | 0.75 | NOD1 (0.42) | NOD1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL11152574 | 0.72 | SIRT2 (0.48) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL11148341 | 0.71 | NOD1 (0.46) | NOD1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL20942845 | 0.65 | ADRB2 (0.57) | ALDH1A1JMJD6ADRB2ADRB1ADRB3 | |
| SCHEMBL11148680 | 0.63 | SMN1; SMN2 (0.39) | NOD1HPGDMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316021-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1982-02-16 | — | — | US | disclosed |
| US-4243813-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1981-01-06 | — | — | US | disclosed |
| US-4196125-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1980-04-01 | — | — | US | disclosed |
| US-4118573-A | ANTIVIRAL AGENTS | ELI LILLY AND COMPANY (US) | 1978-10-03 | — | — | US | disclosed |
| US-4018790-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1977-04-19 | — | — | US | disclosed |