Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | ALDH2 | P05091 | 6/20 | 0.48 |
| ▸ | ALDH3A1 | P30838 | 6/20 | 0.48 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11147987 | 0.85 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1MAPTHPGDALOX15 | |
| SCHEMBL16047437 | 0.83 | ALDH1A1 (0.49) | ALDH1A1ALDH2ALDH3A1CASP3CASP7 | |
| SCHEMBL11154283 | 0.81 | CHRM5 (0.53) | ALDH1A1ALDH2ALDH3A1L3MBTL1MAPT | |
| SCHEMBL4624339 | 0.79 | ALDH3A1 (0.54) | ALDH1A1ALDH2ALDH3A1CHRM5CHRM3 | |
| SCHEMBL18954646 | 0.76 | ALDH1A1 (0.45) | ALDH1A1ALDH2ALDH3A1CASP3CASP7 | |
| SCHEMBL11150299 | 0.75 | ALDH1A1 (0.63) | ALDH1A1ALDH2ALDH3A1L3MBTL1MAPT | |
| SCHEMBL4625371 | 0.75 | ALDH1A1 (0.48) | ALDH1A1ALDH2ALDH3A1CASP3L3MBTL1 | |
| SCHEMBL11147982 | 0.74 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1MAPTHPGDALOX15 | |
| SCHEMBL18954460 | 0.73 | ALDH1A1 (0.47) | ALDH1A1ALDH2ALDH3A1L3MBTL1MAPT | |
| SCHEMBL11148915 | 0.71 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1MAPTHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4382934-A | ANTIALLERGENS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-05-10 | — | — | US | disclosed |
| EP-0010398-B1 | ISATIN DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-04-27 | — | — | EP | disclosed |
| EP-0010398-A1 | Isatin derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-04-30 | — | — | EP | disclosed |