Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 3/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.49 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3023996 | 0.84 | CES1 (0.61) | CHRM5CHRM3L3MBTL1ALDH1A1ALDH3A1 | |
| SCHEMBL11149035 | 0.83 | ALDH1A1 (0.69) | L3MBTL1ALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL11148681 | 0.81 | ALDH1A1 (0.48) | CHRM5CHRM3L3MBTL1ALDH1A1ALDH3A1 | |
| SCHEMBL28026197 | 0.79 | CHRM5 (0.61) | CHRM5CHRM3L3MBTL1ALDH1A1ALDH3A1 | |
| SCHEMBL18954556 | 0.76 | ALDH1A1 (0.57) | CHRM5CHRM3L3MBTL1ALDH1A1ALDH3A1 | |
| SCHEMBL30967409 | 0.76 | CHRM5 (0.70) | CHRM5CHRM3ALDH1A1ALDH3A1MAPT | |
| SCHEMBL2149622 | 0.76 | CES1 (0.73) | CHRM5CHRM3ALDH1A1ALDH3A1BCHE | |
| SCHEMBL12930236 | 0.75 | TRPA1 (0.64) | CHRM5CHRM3L3MBTL1ALDH1A1ALDH3A1 | |
| SCHEMBL28026196 | 0.75 | CHRM5 (0.72) | CHRM5CHRM3ALDH1A1ALDH3A1MAPT | |
| SCHEMBL11148289 | 0.75 | ALDH1A1 (0.43) | L3MBTL1ALDH1A1ALDH3A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4382934-A | ANTIALLERGENS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-05-10 | — | — | US | disclosed |
| EP-0010398-B1 | ISATIN DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-04-27 | — | — | EP | disclosed |
| EP-0010398-A1 | Isatin derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-04-30 | — | — | EP | disclosed |